Results 91 to 100 of about 560,412 (358)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Meta-analysis of the origin of bimaturism in orangutan males [PDF]
, 2017 Unlike any other primate species, orangutans exhibit extraordinary sexual differences in their facial morphology. Two different strategies are available for males that reach sexual maturity: either become fully “flanged” and develop secondary sexual ...
Adnan, Mina
core +1 more source
Breeding ecology of the southern shrike (Lanius meridionalis) in an agrosystem of south-eastern Spain: The surprisingly excellent breeding success in a declining population [PDF]
, 2016 The southern shrike (Lanius meridionalis) is declining at the Spanish and European level. One cause of this decline could be low reproductive success due to low availability of prey in agricultural environments.
Abril-Colón, I. +6 more
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Divergent artificial selection for female reproductive investment has a sexually concordant effect on male reproductive success [PDF]
, 2017 This is the final version of the article. Available from Wiley via the DOI in this record.Depending on the genetic architecture of male and female fitness, sex-specific selection can have negative, positive, or neutral consequences for the opposite sex ...
Bates +47 more
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Survival of the Richest: The Malthusian Mechanism in Pre-Industrial England [PDF]
Fundamental to the Malthusian model of pre-industrial society is the assumption that higher income increased reproductive success. Despite the seemingly inescapable logic of this model, the empirical support for this vital assumption in the preindustrial
Gillian Hamilton, Gregory Clark
core
Genetic structure and seed germination in Portuguese populations of Cheirolophus uliginosus (Asteraceae): Implications for conservation strategies [PDF]
, 2018 Cheirolophus uliginosus is a threatened species, endemic to the Atlantic coast of the Iberian Peninsula, where it occupies a few restricted localities.
Garnatje i Roca, Teresa +3 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Ciencias Marinas, 2019 Fine-scale site fidelity in polygynous pinnipeds influences individual interactions, social stability, and gene flow; over time, demographic processes may be altered, and local extinction of some colonies may occur.
Andrea Rayas-Estrada +1 more
doaj +1 more source