Results 71 to 80 of about 168,765 (262)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

High Frequency Haplotypes are Expected Events, not Historical Figures [version 2; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2016
Cultural transmission of reproductive success states that successful men have more children and pass this raised fecundity to their offspring. Balaresque and colleagues found high frequency haplotypes in a Central Asian Y chromosome dataset, which they ...
Elsa G. Guillot, Murray P. Cox
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Correlates of reproductive success in a Caribbean village [PDF]

open access: yesHuman Ecology, 1986
Genealogical, demographic, and economic data collected in a rural Trinidadian village indicate that: (1) individuals with more land have more offspring, (2) males with more land have higher mating success, (3) young adults with parents resident in the village have higher reproductive success, and (4) the residence of father has a strong effect on young
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Staying Alive: Individual Behavioral Variation Influences Survival, but Not Reproductive Success, in Female Group‐Living Ground Squirrels

open access: yesEcology and Evolution
Animals living in harsh or unpredictable environments adopt adaptive strategies to improve their fitness, with behavioral variation playing a key role in shaping individual outcomes.
Miyako H. Warrington   +4 more
doaj   +1 more source

Species‐level repertoire size predicts a correlation between individual song elaboration and reproductive success

open access: yesEcology and Evolution, 2019
Birdsong has long been considered a sexually selected trait that relays honest information about male quality, and laboratory studies generally suggest that female songbirds prefer larger repertoires.
Cristina M. Robinson, Nicole Creanza
doaj   +1 more source

Status effects on men's reproductive success [PDF]

open access: yesProceedings of the National Academy of Sciences, 2016
Attempts to gain or maintain status are ubiquitous in human social groups, and are particularly evident among men (1). Status rivalries and maneuvers are a common theme in literary works, and of course are amply described and theorized in the social sciences.
openaire   +2 more sources

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Can the reproductive system of a rare and narrowly endemic plant species explain its high genetic diversity?

open access: yesActa Botânica Brasílica, 2018
The reproductive system of flowering plants can be highly variable, affecting their biology, gene flow and genetic variability among populations. Petunia secreta is a rare annual endemic species of Pedra do Segredo, located in the municipality of ...
Daniele M. Rodrigues   +3 more
doaj   +1 more source

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