Results 171 to 180 of about 626,055 (306)

The Impact of Aid on Maternal and Reproductive Health: A Systematic Review to Evaluate the Effect of Aid on the outcomes of Millennium Development Goal 5:The Impact of Aid on Maternal and Reproductive Health

, 2011
BackgroundThe Millennium Development Goal 5 (MDG 5) aims to improve maternal andreproductive health outcomes by: a) reducing the maternal mortality ratio by 75%; and b) achieving universal access to reproductive healthcare, by 2015.
Harper, Ian, Crawford, Fay, Taylor, Emma Michelle, Jeffery, Patricia, Hayman, Rachel, Smith, James   +5 more
core  

Changes in reproductive system in Indian female students in middle altitude conditions. [PDF]

JBRA Assist Reprod
Atykanov A, Imetkulova Z, Abdurakhmanova A, Abdyldaeva N, Isakova A.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Male Reproductive System

The overall reproductive process consists of both the human sex organs which include the male and female reproductive system. The ability to produce offsprings that have similar characteristic as their parents is the goal of reproduction. The sexual type
Assi, Mohammed Abdulrazzaq, Rajion, Mohammed Ali, Mohd Yusoff, Md Sabri, Haron, Abdul Wahid, Mohd Noor, Mohd Hezmee   +4 more
core  

Comprehensive Insight into the Male Dog Reproductive System in Health and Diseases: Developmental, Genetic, and Environmental Factors-Review on Research and Clinical Trials. [PDF]

Vet Sci
Turkmen A, Lonc G, Yurdakok-Dikmen B, Tekin K, Gil D, Zarzycka M, Kania K, Kotula-Balak M.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Applications and challenges of 3D printing in female reproductive system research. [PDF]

3D Print Med
Setareyi R, Khoshandam A, Kianirad S, Saadatmand M, Naji M.   +4 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Reproduction and Sex in the Androdioecious Barnacle <i>Scalpellum scalpellum</i>: Darwin's Model for Studying Reproductive System Evolution. [PDF]

Zool Stud
Høeg JT, Dreyer N, Yusa Y.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source