Results 51 to 60 of about 6,480,186 (210)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
2011 Assisted Reproductive Technology National Summary Report [PDF]
The data for this national report come from the 451 fertility clinics in operation in 2011 that provided and verified data on the outcomes of all ART cycles started in their clinics.
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Ethical objections to sex selection for nonmedical reasons [PDF]
, 2008 This paper examines the main ethical argument used to support the use of sex selection for non-medical reasons, namely that sex selection for non-medical reasons should be allowed on the grounds of reproductive autonomy.
Frith, Lucy; id_orcid +3 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
2015 Assisted Reproductive Technology National Summary Report [PDF]
The data for this national report come from the 464 fertility clinics in operation in 2015 that provided and verified data on the outcomes of all ART cycles started in their clinics. Of the 231,936 ART cycles performed in 2015 at these reporting clinics,
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Inequalities in Reproductive Health: What is the Challenge for Social Work and How Can It Respond? [PDF]
, 2008 Summary: The purpose of this article is to identify contemporary reproductive health issues and the role of social work in combating them. It draws on an extensive range of sources to overview key reproductive health concerns currently facing millions of
Blyth, Eric
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
2018 Assisted Reproductive Technology National Summary Report [PDF]
The data for this national report come from the 456 US fertility clinics in operation in 2018 that provided and verified data on the outcomes of all ART cycles started in their clinics.
core
Holistic approach to assisted reproductive technology
, 2023 It is a perfect order that allows the formation of another individual altogether, while the current information is transferred from generation to generation thanks to the fertilization formed by the union of female and male gametes.
Göç, Rümeysa Yilmaz, Demir, Kenan
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source