Results 51 to 60 of about 47,671 (263)

Role of hysteroscopy prior to assisted reproductive techniques

Journal of Gynecological Endoscopy and Surgery, 2009
There have been numerous advances in the area of assisted reproduction. Among the various reasons of implantation failure, intrauterine lesions play an important role.The aim of the present study is to evaluate the role of hysteroscopy prior to any assisted reproductive technique.It is a retrospective study of 292 women who attended our infertility ...
Palshetkar, Nandita, Pai, Hrishikesh, Pisat, Suchita   +2 more
openaire   +3 more sources

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Role of Hysteroscopy Prior to Assisted Reproduction Techniques

Journal of Minimally Invasive Gynecology, 2014
To determine whether diagnostic hysteroscopy before assisted reproduction techniques (ΑRT) in women without known disease of the uterine cavity is necessary.Prospective cohort clinical study.Reproductive medicine clinic.The study group consisted of 217 infertile women attending the Reproductive Clinic for examination before undergoing ART, either in ...
Bakas, P., Hassiakos, D., Grigoriadis, C., Vlahos, N., Liapis, A., Gregoriou, O.   +5 more
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The relationship of sociocultural beliefs and infertile couples' attitude toward reproductive donation: A descriptive-correlational study

International Journal of Reproductive BioMedicine, 2019
Background There are controversial views on accepting a reproductive donation in the world. Objective This study aimed to determine the relationship between the sociocultural beliefs and infertile couples' attitude toward reproductive ...
Robab Latifnejad Roudsari, Hamideh Jafari, Ali Taghipour   +2 more
doaj   +1 more source

Congenital malformations and assisted reproductive technique: Where is assisted reproductive technique taking us?

Journal of Human Reproductive Sciences, 2012
Development of ART has great benefit for millions of couples all over the world and with falling fertility rate there are a growing numbers of children born with the help of ART, it is important to investigate potential risks to these children. IVF-ICSI pregnancies are associated with higher risk for multiple gestation, preterm labor and low birth ...
Sunita Tandulwadkar, Pooja Lodha, Vineeta Kharb   +2 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Effect of Vitamin D Supplementation on Intracytoplasmic Sperm Injection Outcomes: A Randomized Double-Blind Placebo-Controlled Trial [PDF]

International Journal of Fertility and Sterility, 2019
Background Despite numerous studies indicating an imperative role for reproduction, however, the role of Vitamin D supplementation on outcomes of assisted reproductive techniques remains controversial.
Sara Abedi, Mahboubeh Taebi
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source