Results 81 to 90 of about 165,265 (309)

Congenital malformations and assisted reproductive technique: Where is assisted reproductive technique taking us?

Journal of Human Reproductive Sciences, 2012
Development of ART has great benefit for millions of couples all over the world and with falling fertility rate there are a growing numbers of children born with the help of ART, it is important to investigate potential risks to these children. IVF-ICSI pregnancies are associated with higher risk for multiple gestation, preterm labor and low birth ...
Sunita Tandulwadkar, Pooja Lodha, Vineeta Kharb   +2 more
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Relationship between First Trimester 25-Hydroxyvitamin D3 Levels and Second Trimester Femur Length and Their Effects on Birth Weight and Length at Birth: A Preliminary Study

Obstetrics and Gynecology International, 2019
Objective. The main goal of our study was to assess relationships between first trimester 25-hydroxyvitamin D3 levels and infant birthweight and length at birth. Materials and Methods. We conducted a study over our medical records of 154 live-term births
Elif Ganime Aydeniz, Umut Sari, Isil Tekin, Talat Umut Kutlu Dilek   +3 more
doaj   +1 more source

Role of hysteroscopy prior to assisted reproductive techniques

Journal of Gynecological Endoscopy and Surgery, 2009
There have been numerous advances in the area of assisted reproduction. Among the various reasons of implantation failure, intrauterine lesions play an important role.The aim of the present study is to evaluate the role of hysteroscopy prior to any assisted reproductive technique.It is a retrospective study of 292 women who attended our infertility ...
Palshetkar, Nandita, Pai, Hrishikesh, Pisat, Suchita   +2 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]

, 2020
Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core   +1 more source

Risk of cancer after assisted reproduction: a review of the available evidences and guidance to fertility counselors [PDF]

, 2018
Infertile women requiring ovarian stimulation and assisted reproduction techniques (ART) are faced with difficult issues. The fear that using hormones could increase their risk of cancer is the most significant.
Codacci-Pisanelli, G, Del Pup, L, Levi-Setti, P E, Patrizio, P, Peccatori, F A   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Effect of Vitamin D Supplementation on Intracytoplasmic Sperm Injection Outcomes: A Randomized Double-Blind Placebo-Controlled Trial [PDF]

International Journal of Fertility and Sterility, 2019
Background Despite numerous studies indicating an imperative role for reproduction, however, the role of Vitamin D supplementation on outcomes of assisted reproductive techniques remains controversial.
Sara Abedi, Mahboubeh Taebi
doaj   +1 more source

Pictures of lesbian and gay parenthood in Italian sociology. A critical analysis of 30 years of research [PDF]

, 2017
The article analyses sociological research on lesbian and gay parenthood conducted in Italy over the past 30 years. By focusing on the typologies of the homosexual households of the participants in research projects, this work discusses how empirical ...
Trappolin, Luca
core   +1 more source