Results 111 to 120 of about 567,190 (349)

Adolescent Sexual Health and the Dynamics of Oppression: A Call for Cultural Competency [PDF]

, 2003
This paper encourages those who work with youth to understand the impact of prejudice and discrimination on vulnerable adolescents, to assess and address their needs, and to build on their assets.
L. Laura Davis
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A singular relationship: the bonds between gestational carriers and intended parents in surrogacy between Ukraine and Argentina

Salud Colectiva
Surrogacy is a practice that generates controversy, especially in contexts where regulation is scarce or nonexistent. In Argentina, although there is no specific legislation, this practice involves significant judicial mediation and various legal ...
Lucía Ariza, Natacha Salomé Lima
doaj   +1 more source

Assisted conception and Embryo Research with reference to the tenets of Catholic Christianity [PDF]

, 2017
Religion has a considerable influence over the public’s attitudes towards science and technologies. The objective of the paper is to understand the ethical and religious problems concerning the use of embryo for research in assisting conception for ...
Mitra, Piyali
core  

Comment on Cannarella et al. DNA Methylation in Offspring Conceived after Assisted Reproductive Techniques: A Systematic Review and Meta-Analysis. J. Clin. Med. 2022, 11, 5056 [PDF]

, 2022
Bastien Ducreux, Patricia Fauque
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Peer Review #2 of "The relationship between anti-Müllerian hormone (AMH) levels and pregnancy outcomes in patients undergoing assisted reproductive techniques (ART) (v0.3)"

, 2020
Shalini Umarsingh, Jamila Khatoon Adam, Suresh Naidu, Krishna Equal, Suresh Babu, Suresh Babu Naidu Krishna, Shalini Singh, Babu Naidu, Krishna Corresp, Jamila Khatoon, Shalini Umarsingh, Jamila Khatoon, Sse Alson, Bungum Lj, A Giwercman, E Henic, R Anderson, Sm & Nelson, Whb Wallace, M Chang, C Chiang, M T'sang-T'ang Hsieh, Y Soong, K Hsu, E Caroppo, M Matteo, I Schonauer, G Vizziello, A Pasquadibisceglie, A Vitti, G Damato, Didier Dewailly, Claus Yding Andersen, Adam Balen, Frank Broekmans, Nafi Dilaver, Renato Fanchin, Georg Griesinger, Tom Kelsey, Antonio La Marca, Cornelius Lambalk, T Ebner, M Sommergruber, M Moser, O Shebl, E Schreier-Lechner, G Tews, D Gardner, M Iane, J Stevens, W Schoolcraft, M Gobikrushanth, D Purfield, M Colazo, S Butler, Wang Ambrose, D, Aga Grynnerup, A Lindhard, S Sorensen, S Kini, H Li, D Morrell, S Pickering, K Thong, A Kumar, B Kalra, A Patel, I Mcdavid, W Roudebush, C Kunt, G Ozaksit, R Kurt, Anc Gungor, M Kanat-Pektas, S Kilic, A Dede, La Marca, A Sighinolfi, G Radi, D Argento, C Baraldi, E Artenisio, A Stabile, G Volpe, A, La Marca, A Sunkara, S, M Oskayli, N Gulcin, E Ozatman, G Gercel, M Mutus, B Aksu, C Durakbasa, R Palermo, H Park, S Iyu, H Seok   +99 more
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Updating the markers for oocyte quality evaluation: intracellular temperature as a new index

Reproductive Medicine and Biology, 2018
Background The developmental competence of an embryo is principally dictated by the oocyte. Usually, oocyte selection is based on morphological properties; however, all morphological criteria that are currently used for the grading and screening of ...
Yumi Hoshino
doaj   +1 more source

DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]

, 2020
Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core   +1 more source