Results 51 to 60 of about 216,273 (311)

Outpatient paracentesis for Ovarian Hyperstimulation Syndrome: STOP-OHSS feasibility study and RCT Synopsis

open access: yesHealth Technology Assessment
Background Ovarian hyperstimulation syndrome is a potentially serious complication of fertility treatments. Standard care often involves monitoring, then hospitalisation for severe cases.
Mostafa Metwally   +26 more
doaj   +1 more source

From lab to fertility clinic:the welfare of the child and the ethics of introducing new reproductive technologies [PDF]

open access: yes, 2020
This dissertation examines how new reproductive techniques can be introduced in clinical practice in an ethically responsible way. The aim is to provide both professionals in reproductive medicine and legislators with tools to responsibly deal with the ...
Jans, Verna Anna Ardina Maria
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Refining reproductive parameters for modelling sustainability and extinction in hunted primate populations in the Amazon [PDF]

open access: yes, 2014
Funding: Collections were made voluntarily by local people as part of a community conservation project. Some materials were paid for by YAVACUS, a Peruvian NGO.Primates are frequently hunted in Amazonia.
Bowler, Mark   +16 more
core   +1 more source

Reproductive Outcomes of Hysteroscopic Septoplasty Techniques [PDF]

open access: yesJSLS : Journal of the Society of Laparoendoscopic Surgeons, 2015
Since little is known regarding the correlation between different techniques used during hysteroscopic septoplasty and reproductives outcomes, we amied to evaluate the results of two different techniques of hysteroscopic septoplasty (HS).Data were retrospectively reviewed on 49 patients who underwent HS for symptomatic septate uterus from January 1 ...
Dural, Ozlem   +6 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Are specialized sperm function tests clinically useful in planning assisted reproductive technology? [PDF]

open access: yesInternational Brazilian Journal of Urology, 2019
CASE STUDY 40-year-old male patient and 32-year-old female partner, with a history of primary infertility of two years duration. The workup revealed idiopathic mild oligoasthenotheratozoospermia, and no apparent female infertility factors. The couple has
Sandro C. Esteves
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The meaning of repeated assisted reproductive technologies failures experienced of older infertile women

open access: yesFrontiers in Reproductive Health
IntroductionThe trend of older pregnant women and infertile women in South Korea, who are influencing the low birth rate, is on the rise. Older infertile women earnestly hoped for pregnancy and persisted in undergoing assisted reproductive technology ...
Hyun Jung Oh, Gisoo Shin
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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