Results 131 to 140 of about 1,210,714 (308)
Feminism, Finance and the Work of Reproduction
, 2017 This article begins to think the groundwork for a revolutionary feminist politics in an era shaped by contemporary finance capital and the increasing financialisation daily life. Conceiving of financialisation as a strategic response to a threat that must be brought under capital’s control through reorganising the exploitation of labour-power, it ...
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Celebrating 40 Years: 2013 Annual Report [PDF]
, 2014 For forty years, the Ms. Foundation for Women has led the charge for women's rights.
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Effects of Early Life Family Events on Women’s Late Life Labour Market Behaviour: An Analysis of the Relationship between Childbearing and Retirement in Western Germany [PDF]
The relationship between a woman’s reproductive history and her entry into retirement is not well-investigated yet. Will mothers exit the workforce earlier than childless women (as they have a weaker labour market orientation; as they are more likely to ...
Karsten Hank
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
High development and fertility: fertility at older reproductive ages and gender equality explain the positive link [PDF]
A fundamental reversal of the traditional fertility-development relationship has occurred in highly developed countries so that further socioeconomic development is no longer associated with decreasing fertility, but with increasing fertility.
Francesco C. Billari +2 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source