Results 141 to 150 of about 205,281 (308)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Author Correction: Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells

Scientific Reports, 2023
Zhicong Chen, Yuchen Liu, Anbang He, Jianfa Li, Mingwei Chen, Yonghao Zhan, Junhao Lin, Chengle Zhuang, Li Liu, Guoping Zhao, Weiren Huang, Zhiming Cai   +11 more
doaj   +1 more source

SUGAR-seq reveals the transcriptome and N-linked glycosylation landscape of mononuclear phagocytes at single-cell resolution in a mouse model of autosomal dominant osteopetrosis type 2

BMC Biology
Background Heterozygous mutation of CLCN7 (R286W) is commonly found in patients with benign autosomal dominant osteopetrosis. However, there is no evidence from animal models to confirm that it is a disease mutation.
Yu Sha, Lingyu Huang, Lei Zhang, Xianliang Hou, Chune Mo, Cuiping Pan, Gengshuo Chen, Sha Luo, Minglin Ou   +8 more
doaj   +1 more source

Cellular stress responses and metabolic reprogramming in cancer progression and dormancy

, 2021
Kyle K. Payne
openalex   +2 more sources

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Harmful or Not: Trichostatin A treatment of embryos generated by ICSI or ROSI

Open Life Sciences, 2006
Kishigami Satoshi, Ohta Hiroshi, Mizutani Eiji, Wakayama Sayaka, Bui Hong-Thuy, Thuan Nguyen, Hikichi Takafusa, Suetsugu Rinako, Wakayama Teruhiko   +8 more
doaj   +1 more source

Exploring molecular and cellular signaling pathways: Unraveling the pathogenesis of tendinopathy

Journal of Orthopaedic Translation
Despite the long healing duration of tendon injuries, the outcomes of repairs are frequently suboptimal, resulting in persistent pain and reduced functionality.
Zihan Xu, Wenjing Hou, Tao Zhang, Rui Chen, Thomas Skutella   +4 more
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Efficient Rebalancing of ROS Levels in Plants Links to Temporarily Enhanced Aerobic Fermentation, Distinct Cell Restructuration, and Resilience in Field [PDF]

Innovations in Digital Health, Diagnostics, and Biomarkers, 2022
Birgit Arnholdt-Schmitt, Shahid Aziz, José Hélio Costa   +2 more
doaj   +1 more source

P084 <break /> Airway basal cells of patients with IPF are epigenetically reprogrammed and promote fibrosis [PDF]

, 2016
Antje Prasse, Benedikt Jäger, Victoria Wirtz, Alfonso Carleo, Naftali Kaminski   +4 more
openalex   +1 more source