Results 201 to 210 of about 358,538 (335)

Supplementary Figure S5 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma [PDF]

Abdullah A. Osman, Emre Arslan, Mason Bartels, Chieko Michikawa, Antje Lindemann, Katarzyna Tomczak, Wangjie Yu, Vlad C. Sandulache, Wenmin Ma, Li Shen, Jing Wang, Anand K. Singh, Mitchell J. Frederick, Nakia D. Spencer, Jeffrey J. Kovacs, Timothy P. Heffernan, W. Fraser Symmans, Kunal Rai, Jeffrey N. Myers   +18 more
openalex   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Innate immune overactivation hinders nuclear reprogramming through IFN-IFNAR1 axis. [PDF]

Biochem Biophys Rep
Song Z, Wang Y, Zhang Y, Chen J, Zhang T, Meng S.   +5 more
europepmc   +1 more source

Short-term and long-term high-fat diet promote metabolic disorder through reprogramming mRNA m6A in white adipose tissue by gut microbiota

Youhua Liu, Jiaqi Liu, Ruiti Ren, Zimeng Xin, Yaojun Luo, Yushi Chen, Chaoqun Huang, Yuxi Liu, Tongyudan Yang, Xinxia Wang   +9 more
openalex   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Recent trend on sarcoma stem cell reprogramming towards study of disease progression: A systematic review. [PDF]

J Stem Cells Regen Med
Zulkifli NS, Ab-Rahim S, Muhamad M.
europepmc   +1 more source

3D structure prediction of OCT 4, an important Reprogramming Factor of induced Pluripotent Stem Cells (iPSCs) [PDF]

, 2018
Prashali Chauhan, N. Wal
openalex   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Research progress on glycolytic reprogramming in ophthalmic diseases. [PDF]

PeerJ
Gong X, Feng J, Han Y, Tang G, Yin Y, Li J, Liu Y, Zhang J, Song J, Bi H.   +9 more
europepmc   +1 more source

End-of-the-line urbanism: reprogramming the FEW-nexus of the city region for a post-carbon society

, 2020
Sean P. Cullen, Greg Keeffe, Kevin Logan, Emma Campbell   +3 more
openalex   +1 more source