Results 231 to 240 of about 203,912 (269)
Some of the next articles are maybe not open access.
Regeneration and reprogramming
Current Opinion in Genetics & Development, 2012Recent reprogramming studies indicate that mammalian, somatic cells have the potential to achieve pluripotent states and undergo cell type switching. Such cellular traits are observed under natural conditions in animals that regenerate complex organs. A number of invertebrates display the amazing trait of whole body regeneration.
Dunja, Knapp, Elly M, Tanaka
openaire +2 more sources
Advances in Reprogramming to Pluripotency
Current Stem Cell Research & Therapy, 2015Pluripotent stem cells (PSCs) derived from somatic cells represent a powerful experimental tool for investigating the molecular mechanisms underlying the disease phenotype; with prospects to advance medical therapies. They also have significant potential as a renewable source of autologous cells for cellular therapy.
Alateeq, Suad +2 more
openaire +5 more sources
2006
The concept of reprogramming a cell is very intriguing and has immense therapeutic potential. Examples from physiology and developmental biology suggest that it may well be possible. Experimental approaches are beginning to suggest this also, in particular the initially astonishing accomplishment of somatic cell nuclear transfer and cloning.
openaire +2 more sources
The concept of reprogramming a cell is very intriguing and has immense therapeutic potential. Examples from physiology and developmental biology suggest that it may well be possible. Experimental approaches are beginning to suggest this also, in particular the initially astonishing accomplishment of somatic cell nuclear transfer and cloning.
openaire +2 more sources
Epigenetic Reprogramming in Atherosclerosis
Current Atherosclerosis Reports, 2014Recent data support the involvement of epigenetic alterations in the pathogenesis of atherosclerosis. The most widely investigated epigenetic mechanism is DNA methylation although also histone code changes occur during the diverse steps of atherosclerosis, such as endothelial cell proliferation, vascular smooth muscle cell (SMC) differentiation, and ...
Grimaldi V +7 more
openaire +2 more sources
2019
Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
openaire +2 more sources
Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
openaire +2 more sources
Current Opinion in Genetics & Development, 2012
Martin F, Pera, Kathrin, Plath
openaire +2 more sources
Martin F, Pera, Kathrin, Plath
openaire +2 more sources
Direct cell reprogramming: approaches, mechanisms and progress
Nature Reviews Molecular Cell Biology, 2021Yuchen Yang, Li Qian, Haofei Wang
exaly
Nuclear Reprogramming: An Overview
2006Nuclear reprogramming is an intriguing phenomenon, in which specialized somatic cells reacquire pluripotency through the global resetting of epigenetic modifications without changes occurring to their nuclear DNA information. The nuclear reprogramming activity retained by unfertilized eggs and embryonic stem cells is readily observable through the ...
openaire +2 more sources
Chemical reprogramming of human somatic cells to pluripotent stem cells
Nature, 2022Meng Gaofan, Cheng Li, Lin Cheng
exaly