Results 311 to 320 of about 358,538 (335)
Lineage Plasticity and Histologic Transformation in EGFR-TKI Resistant Lung Cancer. [PDF]
Int J Mol SciLau LYE, Skanderup AJ, Tan AC.
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Critical Reviews in Biochemistry and Molecular Biology, 2012
Cellular reprogramming involves the artificial dedifferentiation of somatic cells to a pluripotent state. When affected by overexpressing specific transcription factors, the process is highly inefficient, as only 0.1-1% of cells typically undergo the transformation.
Ehrensberger AH, Svejstrup JQ
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Cellular reprogramming involves the artificial dedifferentiation of somatic cells to a pluripotent state. When affected by overexpressing specific transcription factors, the process is highly inefficient, as only 0.1-1% of cells typically undergo the transformation.
Ehrensberger AH, Svejstrup JQ
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Cold Spring Harbor Perspectives in Biology, 2021
Embryonic development and cell specification have been viewed as an epigenetically rigid process. Through accumulation of irreversible epigenetic marks, the differentiation process has been considered unidirectional, and once completed cell specification would be permanent and stable.
Hannah, Shelby +2 more
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Embryonic development and cell specification have been viewed as an epigenetically rigid process. Through accumulation of irreversible epigenetic marks, the differentiation process has been considered unidirectional, and once completed cell specification would be permanent and stable.
Hannah, Shelby +2 more
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Science, 2017
Prostate cancer cells alter identity to resist ...
Kathleen, Kelly, Steven P, Balk
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Prostate cancer cells alter identity to resist ...
Kathleen, Kelly, Steven P, Balk
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2006
The concept of reprogramming a cell is very intriguing and has immense therapeutic potential. Examples from physiology and developmental biology suggest that it may well be possible. Experimental approaches are beginning to suggest this also, in particular the initially astonishing accomplishment of somatic cell nuclear transfer and cloning.
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The concept of reprogramming a cell is very intriguing and has immense therapeutic potential. Examples from physiology and developmental biology suggest that it may well be possible. Experimental approaches are beginning to suggest this also, in particular the initially astonishing accomplishment of somatic cell nuclear transfer and cloning.
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2019
Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
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Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
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Regeneration and reprogramming
Current Opinion in Genetics & Development, 2012Recent reprogramming studies indicate that mammalian, somatic cells have the potential to achieve pluripotent states and undergo cell type switching. Such cellular traits are observed under natural conditions in animals that regenerate complex organs. A number of invertebrates display the amazing trait of whole body regeneration.
Dunja, Knapp, Elly M, Tanaka
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Science, 2008
This video introduction to Science's year-end special issue features Shinya Yamanaka of Kyoto University, George Daley of Harvard University, and Science's Gretchen Vogel reviewing some of the work that led studies in reprogramming cells to be tagged the top scientific story for 2008.
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This video introduction to Science's year-end special issue features Shinya Yamanaka of Kyoto University, George Daley of Harvard University, and Science's Gretchen Vogel reviewing some of the work that led studies in reprogramming cells to be tagged the top scientific story for 2008.
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2015
Nuclear reprogramming: Methods and Protocols, Second Edition includes not only classic methods to perform nuclear transfer in different species but also several techniques to assess the early and late development of the reconstructed embryo, at the cellular, molecular, and epigenetic level.
Beaujean, Nathalie +2 more
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Nuclear reprogramming: Methods and Protocols, Second Edition includes not only classic methods to perform nuclear transfer in different species but also several techniques to assess the early and late development of the reconstructed embryo, at the cellular, molecular, and epigenetic level.
Beaujean, Nathalie +2 more
openaire +2 more sources