Results 211 to 220 of about 139,385 (306)

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Correction to "Activate 1-TM Channel of Disordered Rock Salts via Electrostatic Repulsion Regulation for Enhanced Lithium Storage". [PDF]

Angew Chem Int Ed Engl
europepmc   +1 more source

Disentangling Electronic Interactions in f7 Systems: A Comparative Study on GdIII, TbIV, CmIII, and BkIV. [PDF]

Inorg Chem
Studvick CM, Popov IA, Celis-Barros C.
europepmc   +1 more source

Anion‐Driven Surface Reconstruction Enables Direct Regeneration of LiCoO2 Cathode Material

Advanced Science, EarlyView.
The anion scpecies in molten salt systems critically govern the surface reconstruction of regenerated LiCoO2. LiOH−LiCl flux, featuring strong Cl− adsorption and facile dissociation, directs preferential relithiation on (003) facets and forms a Li−O enriched interface.
Mengting Zheng, Shangshu Qian, Meng Li, Shanqing Zhang, Jun Lu   +4 more
wiley   +1 more source

Thin but Strong Versus Thick but Soft: Contrasting Interfacial Water Barriers on Zwitterionic and Nonionic Antibiofouling Self-Assembled Monolayers. [PDF]

J Phys Chem B
Zhao Z, Mendoza Zamarripa EM, Morita S, Mondarte EAQ, Chang R, Chiang CY, Hayashi T.   +6 more
europepmc   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Preparation and Phase Transition Study of a Multi-Environmentally Sensitive Hydrogel. [PDF]

Gels
Wang B, Liu F, Zhai L, Zhang Y, Tian H, Pan Y, Liu F.   +6 more
europepmc   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source

Morphology-Controlled Ultralow Aqueous Friction in Cationic-Anionic Mixed Surfactant Systems. [PDF]

Langmuir
Zhu L, Kampf N, Tian M, Zhang Q, Fan Y, Wang Y, Klein J.   +6 more
europepmc   +1 more source

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source