Results 111 to 120 of about 4,931,670 (329)
Revista Brasileira de Zootecnia, 1999 Os efeitos de diferentes níveis de concentrado nas rações sobre as exigências líquidas de Ca, P, Mg, Na e K foram estudados. Vinte e nove bovinos F1 Nelore x Simental, machos não-castrados, com, em média, 17 meses de idade e 354 kg PV inicial, foram ...
Marcelo de Andrade Ferreira +6 more
doaj
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Veterinary SciencesVitamins A and E are vital fat-soluble micronutrients with distinct yet intertwined roles in various biological processes. This review delves into their functions, nutritional requirements across different animal species, the consequences of deficiencies,
Yauheni Shastak, Wolf Pelletier
doaj +1 more source
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
中西医结合护理Objective To conduct a comprehensive review on the demand status and application scenarios of appropriate techniques in Traditional Chinese Medicine (TCM) nursing among key populations in the community, and provide references for conducting relevant ...
FENG Huiling (冯会玲) +3 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
, 2019 Purpose of this report is the identification and analysis of the regulatory and ethical framework relevant to the SPHINX project. Its findings need therefore to be taken into account by all project partners while executing their tasks. SPHINX aims to introduce a universal cyber security toolkit that will enhance the cyber protection of Health IT ...
Markopoulou, Dimitra +1 more
openaire +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source