Results 211 to 220 of about 7,835,270 (328)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation

Science, 2001
Anders M. Lindroth, Xiaofeng Cao, J. P. Jackson, Daniel Zilberman, C. McCallum, S. Henikoff, S. Jacobsen   +6 more
semanticscholar   +1 more source

The rationale for removing typification from virus taxonomy. [PDF]

Arch Virol
Siddell SG.
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Acute Opioid Tolerance: Intraoperative Remifentanil Increases Postoperative Pain and Morphine Requirement

Anesthesiology, 2000
B. Guignard, A. Bossard, C. Coste, D. Sessler, C. Lebrault, P. Alfonsi, D. Fletcher, M. Chauvin   +7 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis.

Cell, 1997
F. Shalaby, J. Ho, W. Stanford, K. Fischer, A. Schuh, Lois Schwartz, A. Bernstein, Janet Rossant, Janet Rossant   +8 more
semanticscholar   +1 more source

Development and validation of the Tracheostomy‑ProVent score to predict long-term mortality in patients on ventilator care > 21 days: a retrospective cohort study. [PDF]

Respir Res
Jang H, Yoo W, Lee MK, Lee HJ, Hong JM, Kim Y, Lee K.   +6 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Caudal Epidural Steroid Injection in adults with Chronic Lower Backache: Comparison of Landmark-Guided Technique and Ultrasonography-Guided Technique. [PDF]

J Orthop Case Rep
Raina S, Sharma P, Chauhan H, Ghani A, Singh M.   +4 more
europepmc   +1 more source