Results 111 to 120 of about 6,359,917 (289)

Valacyclovir: A Comparative Analysis of Pharmacopoeial Quality Requirements

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Lack of national requirements regulating the quality of valacyclovir hydrochloride active pharmaceutical ingredient (API) in hydrated form and valacyclovir medicinal products may be challenging not only for manufacturers, but also for ...
K. S. Arhipova   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Analysis on the requirements of future data network

open access: yesDianxin kexue, 2019
Internet is the hub of information exchange.The innovation of network technology is the basis and enabler for innovation of new applications and business.The design of the future internet is expected to base on assumptions and visions for a future ...
Xiuli ZHENG   +3 more
doaj   +2 more sources

A practical approach to object based requirements analysis [PDF]

open access: yes
Presented here is an approach developed at the Unisys Houston Operation Division, which supports the early identification of objects. This domain oriented analysis and development concept is based on entity relationship modeling and object data flow ...
Bishop, Michael, Drew, Daniel W.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Image data processing system requirements study. Volume 1: Analysis [PDF]

open access: yes
Digital image processing, image recorders, high-density digital data recorders, and data system element processing for use in an Earth Resources Survey image data processing system are studied.
Honikman, T.   +4 more
core   +1 more source

NASTRAN applications to aircraft propulsion systems [PDF]

open access: yes, 1975
The use of NASTRAN in propulsion system structural integration analysis is described. Computer support programs for modeling, substructuring, and plotting analysis results are discussed.
Beste, D. L., White, J. L.
core   +1 more source

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