Results 131 to 140 of about 6,359,917 (289)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Corporate business analysis as a vital tool for guiding the strategic growth of economic entities
Учёт. Анализ. АудитThe scientific school of corporate business analysis at the Financial University defines business analysis as a systematic process to identify and assess business problems, propose solutions, and support the implementation of change projects.
V. I. Barilenko
doaj +1 more source
Research and Development, Utilization and Labor Requirements: A Dynamic Analysis [PDF]
In this study we have developed a dynamic analysis of a firm under taking plant and equipment and research and development investment,along with labor requirement and P&E utilization decisions. It is shown that in the short run increases in R&D cause the
Jeffrey I. Bernstein, M. Ishaq Nadiri
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Teaching Management at Technical Universities, Business Reality in the Academic Environment
Acta Polytechnica, 2012 Students of technical universities often do not understand why their studies should include learning management skills (in addition to the study of economics).
V. Baroch +3 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Turkish Journal of Nephrology, 2019 OBJECTIVE: Despite of similar body weight and body mass index patients might have different body composition. Our aim was to analyze the relationship between Hb variability, rHuEPO requirements and body composition analysis of MHD patients ...
Emre TUTAL +6 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source