Results 111 to 120 of about 3,794,962 (338)
Formal Requirements Elicitation with FRET [PDF]
FRET is a tool for writing, understanding, formalizing and analyzing requirements. Users write requirements in an intuitive, restricted natural language, called FRETISH, with precise, unambiguous meaning.
Giannakopoulou, Dimitra +5 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
In search of requirements analyst characteristics that influence requirements elicitation effectiveness: a quasi-experiment [PDF]
, 2012 Context: Elicitation effectiveness depends on non-wellunderstood analyst?s skills and abilities. Identifying which analysts? characteristics have stronger influence on elicitation may help to improve requirements quality. Objective: Identify the analysts?
Aranda López King, Alejandrina +2 more
core
Revisiting Requirements Elicitation Techniques
International Journal of Computer Applications, 2013 The importance of Requirements Engineering (RE) has been well recognized by the research community in the last decade. There is no doubt to say that requirements phase is the foundation of the entire Software Development Life Cycle (SDLC) on which the entire software is built.
S. K. Pandey, Shreta Sharma
openaire +1 more source
FAME: Supporting Continuous Requirements Elicitation by Combining User Feedback and Monitoring
IEEE International Requirements Engineering Conference, 2018 Context: Software evolution ensures that software systems in use stay up to date and provide value for end-users. However, it is challenging for requirements engineers to continuously elicit needs for systems used by heterogeneous end-users who are out ...
Marc Oriol +9 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
A cost effective communication model for requirements elicitation in global software development. [PDF]
Sci Rep, 2023 Rauf MA +6 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Design Requirements for a Teledermatology Scale-up Framework
South African Computer Journal, 2018 The value proposition of full-scale teledermatology is evidenced in the literature. The public health sector of South Africa’s KwaZulu-Natal province began synchronous teledermatology in 2003, followed by spontaneous asynchronous (mobile) teledermatology
Laticha EM Walters +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source