Results 101 to 110 of about 90,563 (342)
A Necessity-Based Method for Product Requirement Elicitation and Classification [PDF]
, 2016 A new necessity-based method for the elicitation and classification of requirements in the early phases of the product design process is presented. The purpose is to guide a design engineer through the process of requirement elicitation so as to compile ...
Bojan Dolšak, Špela Brglez
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Arguing satisfaction of security requirements [PDF]
, 2006 This chapter presents a process for security requirements elicitation and analysis, based around the construction of a satisfaction argument for the security of a system. The process starts with the enumeration of security goals based on assets in the
Haley, Charles B. +3 more
core
An Efficient Algorithm for Monitoring Practical TPTL Specifications
, 2016 We provide a dynamic programming algorithm for the monitoring of a fragment of Timed Propositional Temporal Logic (TPTL) specifications. This fragment of TPTL, which is more expressive than Metric Temporal Logic, is characterized by independent time ...
Dokhanchi, Adel +3 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Design Requirements for a Teledermatology Scale-up Framework
South African Computer Journal, 2018 The value proposition of full-scale teledermatology is evidenced in the literature. The public health sector of South Africa’s KwaZulu-Natal province began synchronous teledermatology in 2003, followed by spontaneous asynchronous (mobile) teledermatology
Laticha EM Walters +2 more
doaj +1 more source
Collaborative mint map tool to facilitate requirement elicitation [PDF]
, 2011 Requirements elicitation is a crucial task in any software development process.It is notable as a major contributor to the project failure.To minimize and subsequently improve the process, folding Mind Map concept in the elicitation process and ...
Abdul Hamid, Nazatul Naquiah Ahba +2 more
core
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Revisiting Requirements Elicitation Techniques
International Journal of Computer Applications, 2013 The importance of Requirements Engineering (RE) has been well recognized by the research community in the last decade. There is no doubt to say that requirements phase is the foundation of the entire Software Development Life Cycle (SDLC) on which the entire software is built.
S. K. Pandey, Shreta Sharma
openaire +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source