Results 71 to 80 of about 3,794,962 (338)

Influence of Context on Decision Making during Requirements Elicitation [PDF]

, 2012
Requirements engineers should strive to get a better insight into decision making processes. During elicitation of requirements, decision making influences how stakeholders communicate with engineers, thereby affecting the engineers' understanding of ...
Burnay, Corentin, Faulkner, Stéphane, Jureta, Ivan   +2 more
core   +2 more sources

Anticipating Requirements Changes-Using Futurology in Requirements Elicitation

International Journal of Information System Modeling and Design, 2012
It is well known that requirements changes in a later phase of software developments is a major source of software defects and costs. Thus, the need of techniques to control or reduce the amount of changes during software development projects. The authors advocate the use of foresight methods as a valuable input to requirements elicitation, with the ...
Pimentel, João Henrique, Santos, Emanuel, Castro, Jaelson, Franch Gutiérrez, Javier   +3 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Integrating Users Logic Into Requirements Engineering for Connected Healthcare co-Design [PDF]

, 2019
The ongoing transformation in healthcare requires the creation of agile systems to meet the growing needs of patients. An approach to develop such systems requires the elicitation of end-users’ perspectives to software development life circle.
Isomursu, Minna, Karampela, Maria, Ouhbi, Sofia   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Strategies to Minimize Problems in Global Requirements Elicitation

CLEI Electronic Journal, 2008
Many challenges arise in global software development projects, most of which are related to the lack of face-to-face communication and people’s need to feel comfortable with the technology that they use. In this paper we introduce a methodology to detect
Gabriela N Aranda, Aurora Vizcaíno, Alejandra Cechich, Mario Piattini   +3 more
doaj   +1 more source

Effect of domain knowledge on elicitation effectiveness: an internally replicated controlled experiment [PDF]

, 2016
Context. Requirements elicitation is a highly communicative activity in which human interactions play a critical role. A number of analyst characteristics or skills may influence elicitation process effectiveness. Aim.
Aranda López King, Alejandrina, Dieste Tubio, Oscar, Juristo Juzgado, Natalia   +2 more
core   +2 more sources

Requirements elicitation techniques: a systematic literature review based on the maturity of the techniques

IET Software, 2018
Requirements elicitation is a critical activity that forms part of the requirements engineering process because it has to discover what the software must do through a solid understanding of the wishes and needs of the various stakeholders and to ...
C. Pacheco, I. García, Miryam Reyes
semanticscholar   +1 more source

SafeSec Tropos: Joint security and safety requirements elicitation

Comput. Stand. Interfaces, 2020
The growing convergence of information technology with operational technology and the accordant proliferation of interconnected cyber-physical systems (CPSs) has given rise to several security and safety challenges.
Georgios Kavallieratos, S. Katsikas, Vasileios Gkioulos   +2 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source