Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Towards dealing with commonly occurring requirements engineering process issues during software development outsourcing. [PDF]
Iqbal J +4 more
europepmc +1 more source
Specifying and Reasoning about Contextual Preferences in the Goal-oriented Requirements Modelling
Goal-oriented requirements variability modelling has established the understanding for adaptability in the early stage of software development-the Requirements Engineering phase.
Bai, Quan +4 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Requirements Engineering Quality: a Literature Review
Requirements Engineering Quality (REQ) has a large influence on the success of a software project. A systematic literature review (SLR) is conducted to get complete information about REQ.
Rosa Delima, Azhari, Khabib Mustofa
doaj +1 more source
Towards ubiquitous requirements engineering through recommendations based on context histories. [PDF]
Lima R +4 more
europepmc +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Model-Based Requirements Management in Gear Systems Design Based On Graph-Based Design Languages
For several decades, a wide-spread consensus concerning the enormous importance of an in-depth clarification of the specifications of a product has been observed. A weak clarification of specifications is repeatedly listed as a main cause for the failure
Kevin Holder +6 more
doaj +1 more source
Creating an Intercultural User-Centric Design for a Digital Sexual Health Education App for Young Women in Resource-Poor Regions of Kenya: Qualitative Self-Extended Double Diamond Model for Requirements Engineering Analysis. [PDF]
Soehnchen C +4 more
europepmc +1 more source
Teaching Motivational Models in Agile Requirements Engineering
Software engineering courses continually strive to maintain an excellent teaching curriculum that provides students with the agile skills as per industry needs.
A. Lopez-Lorca +2 more
semanticscholar +1 more source

