Results 141 to 150 of about 7,965,717 (326)
User-oriented requirements engineering [PDF]
2014 IEEE 2nd International Workshop on Usability and Accessibility Focused Requirements Engineering (UsARE), 2014 A method for analysing emotion and motivation in requirements engineering (RE) is described. The method extends personal RE where requirements are for individual users and their needs. Theories from the psychology of emotion and motivation are introduced and applied in a top-down pathway motivated by system goals to influence users, and a bottom-up ...
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
InformationRecent advances in natural language processing (NLP) have enabled the automation of Software Requirements Classification (SRC), particularly through fine-tuning models such as Bidirectional Encoder Representations from Transformers (BERTs).
Safaa Eltahier +2 more
doaj +1 more source
A Framework for Systematic Refinement of Trustworthiness Requirements
Information, 2017 The trustworthiness of systems that support complex collaborative business processes is an emergent property. In order to address users’ trust concerns, trustworthiness requirements of software systems must be elicited and satisfied.
Nazila Gol Mohammadi, Maritta Heisel
doaj +1 more source
A Comprehensive "Real-World Constraints"-Aware Requirements Engineering Related Assessment and a Critical State-of-the-Art Review of the Monitoring of Humans in Bed. [PDF]
Sensors (Basel), 2022 Kyamakya K +4 more
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
SRE_BBC: A Self-Adaptive Security Enabled Requirements Engineering Approach for SLA Smart Contracts in Blockchain-Based Cloud Systems. [PDF]
Sensors (Basel), 2022 Singh I, Lee SW.
europepmc +1 more source
On the engineering of systems of systems: key challenges for the requirements engineering community! [PDF]
Software intensive systems of the future will be ultra large-scale systems of systems. Systems of Systems Engineering focuses on the interoperation of many independent, self-contained constituent systems to achieve a global need. The scale and complexity
Ncube, Cornelius
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source