Results 31 to 40 of about 344,051 (254)

Computer-Aided Identification and Validation of Privacy Requirements

open access: yesInformation, 2016
Privacy is a software quality that is closely related to security. The main difference is that security properties aim at the protection of assets that are crucial for the considered system, and privacy aims at the protection of personal data that are ...
Rene Meis, Maritta Heisel
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The information activity of rail passenger information staff: a foundation for information system requirements

open access: yesInformation Research: An International Electronic Journal, 2006
Introduction. This paper examines the goal-directed information activity of passenger information staff, working in the dynamic environment of rail network control. The explicit aim is to define a meaningful set of information system requirements.
Martin Rose
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Role of Environmental Assumptions in Shaping Requirements Technical Debt

open access: yesApplied Sciences
Environmental assumptions, which are expectations about a system’s operating context, play a critical yet often underexplored role in the emergence of requirements technical debt (RTD).
Mounifah Alenazi
doaj   +1 more source

Automation of Basketball Match Data Management

open access: yesInformation, 2021
Despite the fact that sport plays a substantial role in people’s lives, funding varies significantly from one discipline to another. For example, in Poland, women’s basketball in the lower divisions, is primarily developing thanks to enthusiasts. The aim
Łukasz Chomątek, Kinga Sierakowska
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

REQUIREMENTS MANAGEMENT TOOL ELEMENTS FOR THE MALAYSIAN SOFTWARE INDUSTRY

open access: yesJournal of ICT, 2012
Developing quality software is becoming a challenge that requires the practitioners to employ appropriate techniques, methodologies and good practices in software engineering.
Azida Zainol, Sa’ad Mansoor
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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