Results 81 to 90 of about 1,067,278 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Extending Behavior Trees for Robotic Missions with Quality Requirements

open access: yes
Context and motivation: In recent years, behavior trees have gained growing interest within the robotics community as a specification and control-switching mechanism for the different tasks that form a robotics mission.
Horkoff, Jennifer,   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Effects of Native Language on Requirements Quality [PDF]

open access: yesAnnals of computer science and information systems, 2023
Fayona Cowperthwaite   +2 more
doaj   +1 more source

Valacyclovir: A Comparative Analysis of Pharmacopoeial Quality Requirements

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Lack of national requirements regulating the quality of valacyclovir hydrochloride active pharmaceutical ingredient (API) in hydrated form and valacyclovir medicinal products may be challenging not only for manufacturers, but also for ...
K. S. Arhipova   +3 more
doaj   +1 more source

ANALYSIS OF THE RELATIONSHIP AMONG TRAINING, SKILLS AND CONTENTEMENT OF THE EMPLOYERS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
Successful designing and implementation of the quality management system in an organization requires taking into account the requirements of all categories of natural persons or legal entities which have direct or indirect interests towards it ...
Roman Teodora   +3 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

SOLUTIONS FOR QUALITY IMPROVEMENT OF UPHOLSTERY AND INTERIOR DESIGN PRODUCTS [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2019
Quality assurance by satisfying the demands of the beneficiaries is the prime objective of any commercial society. The demands of the beneficiary are at the root of the creative and design process, finalized by elaborating the product and process ...
LUTIC Liliana
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Architecting and Coordinating Thousands of Requirements - An Industrial Case Study

open access: yes, 2009
[Context & motivation] When large organizations develop systems for large markets, the size and complexity of the work artefacts of requirements engineering impose critical challenges.
Schrewelius, Claes   +3 more
core  

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