Results 91 to 100 of about 4,368,218 (320)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Printed Electronics in Product Identification and Tracing [PDF]

, 2009
Food and livestock traceability and tracking are now very hot topics because of severe threats to health and the need to comply with stringent new legislation. The traceability of products and components has received critical attention over the past few
Füzesi, István, Herdon, Miklós
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

CRSensor: A Synchronized and Impact-Aware Traceability Framework for Business Application Development

Applied Sciences
To enable effective change impact management in business applications, robust requirements traceability is essential. However, manual approaches are inefficient and prone to errors. While the prior Model-Driven Engineering (MDE)-based research, including
Soojin Park
doaj   +1 more source

A Study on the Effect of Traceability Links in Software Maintenance

IEEE Access, 2013
In software development, stakeholders of the same project often collaborate asynchronously through shared artifacts. A traceability system links a project's artifacts and therefore provides support for collaboration among stakeholders.
Khaled Jaber, Bonita Sharif, Chang Liu
doaj   +1 more source

Change Impact Analysis based on Formalization of Trace Relations for Requirements [PDF]

, 2008
Evolving customer needs is one of the driving factors in software development. There is a need to analyze the impact of requirement changes in order to determine possible conflicts and design alternatives influenced by these changes.
Berg, K.G. van den, Göknil, A., Kurtev, I.   +2 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A Lightweight Accountable Parallel Blockchain Architecture Based on Redactable Blockchain for Agri-Food Traceability

Foods
Agri-food safety issues have received widespread attention globally. The emergence of blockchain technology (BCT) effectively addresses trust issues in the agri-food supply chain traceability system (AFSCTS).
Feng Chen, Chunjiang Zhao, Xinting Yang, Na Luo, Chuanheng Sun   +4 more
doaj   +1 more source

Requirements Quick Notes [PDF]

, 2016
A short introduction to requirements and their role in system development. Includes industry definition of requirements, overview of basic requirements process including numbering of requirements, ties to testing, and traceability.
Honig, William L, Takada, Shingo
core