Results 61 to 70 of about 93,955 (296)

A new model for requirements to code traceability to support code coverage analysis [PDF]

, 2013
Requirements traceability is one of the most important and challenging tasks in the industry to ensure that software has been developed according to all user requirements.
Ibrahim, Suhaimi, Shahid, Muhammad
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

META-MODELING CONSTRUCTS FOR REQUIREMENTS REUSE (RR): SOFTWARE REQUIREMENTS PATTERNS, VARIABILITY AND TRACEABILITY

Malaysian Journal of Computing, 2018
Reuse is a fundamental activity, which increases quality and productivity of software products. Reuse of software artifacts, such as requirements, architectures, and codes can be employed at any developmental stage of software. However, reuse at a higher
Badamasi Imam Ya’u, Azlin Nordin, Norsaremah Salleh
doaj   +1 more source

Change Impact Analysis for SysML Requirements Models based on Semantics of Trace Relations [PDF]

, 2009
Change impact analysis is one of the applications of requirements traceability in software engineering community. In this paper, we focus on requirements and requirements relations from traceability perspective.
Berg, Klaas van den, Goede, Koos de, Göknil, Arda, Hove, David ten, Kurtev, Ivan   +4 more
core   +1 more source

DNA barcoding as a molecular tool to track down mislabeling and food piracy [PDF]

, 2015
DNA barcoding is a molecular technology that allows the identification of any biological species by amplifying, sequencing and querying the information from genic and/or intergenic standardized target regions belonging to the extranuclear genomes ...
Barcaccia, Gianni, Cassandro, Martino, Lucchin, Margherita   +2 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Blockchain for drug traceability: Architectures and open challenges

Health Informatics Journal, 2021
Pharmaceutical supply chain (PSC) consists of multiple stakeholders including raw material suppliers, manufacturers, distributors, regulatory authorities, pharmacies, hospitals, and patients.
Mueen Uddin, Khaled Salah, Raja Jayaraman, Sasa Pesic, Samer Ellahham   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Blockchain-Based Information Security Protection Mechanism for the Traceability of Intellectual Property Transactions

Sensors
Traditional intellectual property transaction traceability has problems such as information asymmetry, traceability information storage methods relying on centralized databases, and easy tampering of transaction information, etc.
Zheng Wang, Wenlong Feng, Mengxing Huang, Siling Feng, Shilong Mo, Yunhong Li   +5 more
doaj   +1 more source

Tool Support for Validation of Formal System Models: Interactive Visualization and Requirements Traceability [PDF]

Electronic Proceedings in Theoretical Computer Science, 2019
Development processes in various engineering disciplines are incorporating formal models to ensure safety properties of critical systems. The use of these formal models requires to reason about their adequacy, i.e., to validate that a model mirrors the ...
Eduard Kamburjan, Jonas Stromberg
doaj   +1 more source