Results 171 to 180 of about 62,723 (246)
Intraoperative respiratory exchange ratio to predict complications after cardiopulmonary bypass surgery: a retrospective cohort study. [PDF]
Riesemann S +10 more
europepmc +1 more source
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha +5 more
wiley +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source
Loss of ovarian hormones modulates sex-specific metabolic adaptations to volumetric muscle loss. [PDF]
Bruzina AS +5 more
europepmc +1 more source
ABSTRACT Bizarre parosteal osteochondromatous proliferation is an exceedingly rare bone tumor that mimics malignant lesions both clinically and radiologically. Atypical imaging findings, such as cortical erosion, may bias the differential diagnosis toward malignant tumors.
Jacobo Kerbel +4 more
wiley +1 more source
Energy expenditure and the accuracy of predictive equations in myotonic dystrophy type 1. [PDF]
Aarts WJA +9 more
europepmc +1 more source
ABSTRACT The impact of cigarette smoking on the cardiorespiratory response to exhaustive exercise remains unclear. This study investigated the smoking effect on exercise tolerance by analyzing the cardiorespiratory and metabolic variables during an exhausting sinusoidal exercise in young physically active smokers (SM) without known cardiovascular and ...
Marta Borrelli +8 more
wiley +1 more source
This work presents multilayer NCM622 cathodes with functionally graded inactive components (binder and carbon black) to evaluate their impact on electrode performance. By separating mechanical and transport contributions through graded architecture, the study identifies performance changes with increasing loading and shows a clear impact at high ...
Fatjon Maxharraj +5 more
wiley +1 more source
Structured Sanda training as an innovative exercise intervention for young men with obesity: metabolic load distribution and adaptive responses compared with moderate-intensity continuous cycling. [PDF]
Chen A, Tian X, Tian M.
europepmc +1 more source

