Results 181 to 190 of about 62,723 (246)

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

open access: yesHead &Neck, Volume 48, Issue 9, Page 2364-2376, September 2026.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam   +10 more
wiley   +1 more source

Rocker Geometry in Running Footwear: A Scoping Review of Definitions, Commercial Descriptors and Outcome Measures

open access: yesJournal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Background Rockered midsoles are increasingly used in running footwear, yet definitions, terminology and outcome measures vary widely across research and commercial sectors. Aim This scoping review mapped how rockers are defined in academic literature, how major footwear brands describe them and which outcome measures are most frequently ...
Priyanka Khusal   +3 more
wiley   +1 more source

Revisiting Enzyme Replacement Therapy for Aspartylglucosaminuria: Truncated Phosphotransferase Enhances Mannose‐6‐Phosphorylation and Cellular Uptake of Aspartylglucosaminidase

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by a deficiency of aspartylglucosaminidase (AGA), a hydrolase involved in the degradation of N‐glycosylated proteins. Currently, no approved therapies are available for AGU. Development of enzyme replacement therapy (ERT) for AGU has been hampered by the complex proteolytic ...
Antje Banning   +3 more
wiley   +1 more source

Chronic exposure to artificial light at night dampens rhythms in locomotor activity, metabolism, and sleep in female mice. [PDF]

open access: yesPhysiol Behav
Meléndez-Fernández OH   +6 more
europepmc   +1 more source

Utility of Exogenous Ketones and Modified Atkins Diet in a Child With GSD VII (Tarui Disease)

open access: yesJIMD Reports, Volume 67, Issue 5, September 2026.
A child with glycogen storage disease VII (Tarui disease) undertook three different diet therapies for 8 weeks each; usual diet, pre‐exercise exogenous ketones (150 mg/kg) and a modified atkins diet. Compared to usual diet, both exogenous ketones and modified atkins diet improved exercise‐induced myopathic symptoms, physical health‐related quality of ...
Kiera Batten   +5 more
wiley   +1 more source

Ultrastructure of Vitellogenic Ovarian Follicles and Morphogenesis of the Oocyte Envelope in the Eurasian Ruffe (Gymnocephalus cernua Linnaeus 1758) (Teleostei, Perciformes)

open access: yesJournal of Morphology, Volume 287, Issue 9, September 2026.
Ruffe's vitellogenic ovarian follicles consists of a single oocyte surrounded by follicular cells, a basal lamina, and thecal cells. The oocytes are polarized and covered by a primary envelope. The follicular cells diversify into micropylar and mainbody cells. The latter have dark and bright cytoplasms.
Monika Żelazowska, Roman Kujawa
wiley   +1 more source

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