Biotechnology and Bioengineering, EarlyView.ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter +10 more
wiley +1 more source
Advancing Gastrointestinal Cancer Risk Prediction With Patient-Centered Machine Learning: Machine Learning Modeling Study. [PDF]
JMIR Med InformBaublyte D, Lee J, Gunathilake M, Kim J.
europepmc +1 more source
Functional Diversity and Oleaginous Potential of Fungal Strains From Hawaiian Soil Ecosystems
Biotechnology and Bioengineering, EarlyView.ABSTRACT Fungi represent an important but underexplored resource for microbial lipid production, including nutritionally valuable polyunsaturated fatty acids. Hawaiian soils, shaped by volcanic parent materials and strong environmental gradients, provide a unique setting for discovering functionally diverse fungal strains with distinct metabolic traits.
Yu Wang +12 more
wiley +1 more source
Dynamic photobiology: A collection of experimental protocols for time-resolved structural studies on light-activated proteins. [PDF]
FEBS Open BioKapetanaki SM, Royant A, Yorke BA.
europepmc +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT SMEs receive increasing institutional support to embed sustainability, yet they vary widely in their ability to translate such support into practice. This study addresses this gap by examining the internal cognitive and strategic mechanism (sustainability orientation) through which managers interpret institutional support and the contextual ...
Michael Zisuh Ngoasong +3 more
wiley +1 more source
Predicting Dropout in Psychotherapy for Major Depressive Disorder: A Machine Learning Approach to Identifying At-Risk Patients. [PDF]
Clin Psychol PsychotherBremer-Hoeve S +5 more
europepmc +1 more source
A Decision‐Making Model for Implementing Green Technology in Sustainable Building Projects
Business Strategy and the Environment, EarlyView.ABSTRACT Green technology (GT) adoption is pivotal for reconciling environmental stewardship with economic viability in the built environment, particularly in resource‐constrained emerging economies. However, empirical evidence on how specific GT drivers actively mitigate adoption barriers remains scarce.
Abdelazim Ibrahim +5 more
wiley +1 more source
Arousal modulates functional connectivity through structured and hemispherically asymmetric community architecture during wakefulness. [PDF]
ElifeKong X, Li S, Gong G.
europepmc +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT Drawing upon ecological modernization theory as the analytical framework, this study employs macro‐level longitudinal tracking data covering China's major regions as research samples. It measures the green and low‐carbon development (GLCD) of manufacturing from the four dimensions—“carbon reduction, pollution mitigation, ecological expansion ...
Deng Wang +4 more
wiley +1 more source
An XGBoost-based predictive framework for diabetes mellitus multi-classification. [PDF]
Sci RepEl Sherbiny MM +4 more
europepmc +1 more source