Results 121 to 130 of about 23,387 (216)

Strain‐Specific Biotransformation of Grape Marc by Lactic Acid Bacteria: Genomic Validation and Gut Microbiota Modulation

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu   +4 more
wiley   +1 more source

Structure–activity relationship study shows versatility in substrate specificity for heterodisulfide reductase in methanogenic archaea

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Hydrogenotrophic methanogens are anaerobic archaea that convert carbon dioxide and hydrogen into methane. Central to this process is the heterodisulfide reductase (Hdr), which catalyzes the reduction of the heterodisulfide made of coenzyme M and coenzyme B. In vivo, Hdr functions in association with electron‐donating modules such as the [NiFe]‐
Mahdi Faal Maleki   +5 more
wiley   +1 more source

Activity profile of the 6 confirmed hit compounds against CHIKV based on resazurin reduction assay.

open access: yes, 2013
Activity profile of the 6 confirmed hit compounds against CHIKV based on resazurin reduction assay.
Benoit Lombardot (478538)   +9 more
core   +1 more source

A Straightforward Synthesis of a Diene From a Homoallylic Bromide to Access Cycloadducts to Elucidate Michael Acceptors as Antimicrobial Motifs

open access: yesChemistrySelect, Volume 11, Issue 25, 3 July 2026.
A straightforward method to cleanly yield a novel diene from isopulegol was developed. The diene served as a precursor to various cycloadducts, which led to the identification of Michael acceptors as antimicrobial motifs. ABSTRACT Conjugated dienes are useful precursors to cascade reactions that undergo cycloadditions to access polycyclic compounds ...
Jose G. Urbiola   +6 more
wiley   +1 more source

Cow Milk Risk Factors Associated With Bacterial Contaminations Along Dairy Value Chain in Lushoto and Handeni Districts, Tanzania

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Milk and milk products are important sources of nutrients to human and animals, but due to its physicochemical characteristics and nutritional value, it serves as an excellent medium for growth of microorganisms. Most of smallholder dairy farmers have no training on livestock husbandry and milk handling practices.
Fortunate Shija, Hezron Emmanuel Nonga
wiley   +1 more source

Passage‐Dependent Size Distributions of Human‐Derived Cells: Implications for Metabolic Assays

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Cell size changes with passage. This propagates into size‐dependent functional readouts, such as metabolic assays. ABSTRACT Biological noise is ubiquitous in living systems; yet, it is often neglected in cell‐based experiments, potentially biasing data interpretation.
Ermes Botte   +3 more
wiley   +1 more source

Total Synthesis and Antimalarial Studies of Caelestines A–C

open access: yesChemMedChem, Volume 21, Issue 11, 15 June 2026.
Total synthesis of caelestines A–C (alkaloids from the Australian ascidian, Aplidium caelestis) was accomplished, constituting the first synthesis of caelestines B and C. Caelestines A–C, with five other novel quinolones, were assessed against Plasmodium falciparum 3D7 and Dd2. Caelestine B was found to be a selective antimalarial alkaloid. Caelestines
Henry S. T. Smith   +3 more
wiley   +1 more source

SPECTROPHOTOMETRIC DETERMINATION OF STABILITY OF RESAZURIN BUTANOL EXTRACTS

open access: yes, 2011
Redukcijski test z resazurinom temelji na sposobnosti metabolično aktivnih semenčic, da reducirajo redoks barvilo resazurin v resorufin. V diplomskem delu smo razvili spektrofotometrično aplikacijo redukcijskega testa z resazurinom za osemenjevalne doze ...
Bogataj, Mateja
core  

In Vitro Biological Activities of Piper corcovadensis C.DC.: Antioxidant, Antineoplastic‐Related and Antibacterial Effects

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Piper corcovadensis extract is rich in bioactive compounds with antioxidant potential, capable of decreasing ROS levels; antitumor activity in cutaneous melanoma cells SK‐MEL‐28; and anti‐inflammatory activity, decreasing the expression of IL‐6 and NLPR3 genes and increasing TNF expression, without cytotoxicity to healthy peripheral blood cells (PBMCs).
Bruno Henrique Fontoura   +7 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, Volume 16, Issue 6, Page 1115-1131, June 2026.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy