Results 101 to 110 of about 24,024 (231)

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Visceral leishmaniasis (VL) is associated with treatment complications due to the continued growth of resistant parasites toward currently available pathogen-directed therapeutics.
M. Shamim Hasan Zahid, Monica M. Johnson, Robert J. Tokarski, II, Abhay R. Satoskar, James R. Fuchs, Eric M. Bachelder, Kristy M. Ainslie   +6 more
doaj   +1 more source

Effect of Moderate Heat on TCE Reductive Dechlorination Rates in Groundwater

Groundwater Monitoring &Remediation, EarlyView.
Abstract Low‐temperature heating (in the mesophilic range of ~15 to 40 °C) of contaminated aquifers offers the prospect of increasing the rates for biotic and abiotic treatment of volatile organic compounds. Thermal In Situ Sustainable Remediation (TISR®) is one of the approaches available to implement low temperature heating.
David L. Freedman, Nicholas Cotter, Craig Divine, Shandra Justicia‐Leone   +3 more
wiley   +1 more source

Drug Sensitivity Assay of Xanthomonas citri subsp. citri Using REMA Plate Method

Bio-Protocol, 2013
Resazurin Microtiter Assay (REMA) is a simple, rapid, reliable, sensitive, safe and cost-effective measurement of cell viability. Resazurin detects cell viability by converting from a nonfluorescent dye to the highly red fluorescent dye resorufin in ...
Isabel Silva, Henrique Ferreira
doaj   +1 more source

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor, Rena E. Mullally, Sarah F. McComish, Julia O'Sullivan, Ian Woods, Ingmar Schoen, Massimiliano Garre, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +9 more
wiley   +1 more source

The Efficacy of Food‐Grade Substances to Protect Dietary Glutamine From Ruminal Degradation

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study was conducted to investigate the use of four, low cost, food‐grade substances to protect glutamine from microbial degradation in vitro, and subsequently validate their efficacy in vivo. Two in vitro trials were conducted using 250 mL bottles replicated in triplicate to test beeswax‐, paraffin wax‐, zein‐, and rice bran wax ...
Lillian P. Carlyon, Tianna R. Boyce, Leesa‐Joy Dunstan, Bruno R. C. Alves, Kiro Petrovski, Mariana Caetano   +5 more
wiley   +1 more source

Rhizobacteria‐Induced Systemic Priming Against Fungal Pathogens Involves Hydroxycinnamic Acid Amides

Plant, Cell &Environment, EarlyView.
ABSTRACT The rhizosphere, a narrow region of soil surrounding roots, contains diverse microorganisms with a composition that is distinct from the surrounding soil. Some rhizosphere bacteria can trigger a heightened state of immunity in the whole plant, termed Induced Systemic Resistance (ISR).
Mackenzie Eli William Loranger, Wolfgang Moeder, Hyunsuh Lee, David K. Liscombe, Eric Déziel, Keiko Yoshioka   +5 more
wiley   +1 more source

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

Photochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira, Bruna Carolina Corrêa, Vanderlei Salvador Bagnato, Kate Cristina Blanco   +3 more
wiley   +1 more source

Detrimental Effect of Low‐Magnitude High‐Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment

JOR SPINE, Volume 9, Issue 2, June 2026.
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen, Felizitas Figel, Franziska Widmayer, Morten Vogt, Maria Ahrens, Hans‐Joachim Wilke, Anita Ignatius, Melanie Haffner‐Luntzer, Cornelia Neidlinger‐Wilke, Graciosa Quelhas Teixeira   +9 more
wiley   +1 more source

The Use of FN‐Silk Networks as Extracellular Matrix‐Mimicking Support for 3D In Vitro Breast Cancer Models Improved the Model's Reproducibility in Drug Sensitivity

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Chemotherapy treatment experiments were conducted on three breast cancer cell lines cultured in 2D, spheroids, and the novel 3D support: FN‐silk networks. The breast cancer cells cultured in FN‐silk networks were generally less sensitive to the drugs tested, compared to 2D cultures, potentially giving higher clinical relevance.
Suha Karrani, Astrid Källén, Caterina Collodet, Serge Ducommun, Mona Widhe, My Hedhammar   +5 more
wiley   +1 more source

Chemical Profiling and Biological Activity of Copaiba Oil‐Resin Samples and Development of HPLC‐DAD Method for the Analysis of β‐Caryophyllene

Biomedical Chromatography, Volume 40, Issue 5, May 2026.
ABSTRACT The Copaifera species are traditionally used for their anti‐inflammatory, antiseptic and healing properties. The objective of this study was to compare the chromatographic profiles of seven samples of copaiba oil‐resin with respect to chromatographic and physicochemical properties and to evaluate their biological activities.
Gabriel de A. P. Graça, Cláudia G. Silva, Denise de O. Scoaris, Juliana Rodrigues de Vasconcelos, André Santos Alkimim, Vanessa C. F. Mosqueira, Luciana S. Salomon, Pietra Piotto Marcellini, Isabelle Renata Martins da Silva, Janete S. C. Santos, Andreia Fonseca Silva, Carolina P. S. Moreira, Júlio C. D. Lopes, Vera L. de Almeida   +13 more
wiley   +1 more source