Results 81 to 90 of about 23,387 (216)

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Antimicrobial Activity Evaluation of Biocidal Surfaces with Resazurin Assay

, 2023
This diploma thesis deals with the determination of antimicrobial activity of surfaces with biocidal effect using the resazurin test. The resazurin method of determination is a non-invasive colorimetric method with great potential for widespread use ...
Patakyová, Sylvia
core   +1 more source

FLUOROMETRIC ASSAY FOR CELL PROLIFERATION IN HUMAN TUMOR CELL LINES APPLICATION

Vitae, 2010
Assessment of in vitro cytotoxicity as a model to explore biological activity of compounds isolated from different sources is the first approached to search molecules with potential anticancer activity.
Linamaría Escobar M., Fabio A. Aristizábal G.   +1 more
doaj  

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Quantifying Benthic Biolayer Contributions to Whole‐Stream Reactivity by Unifying Surface and Subsurface Observations: Field Evidence and Theory

Water Resources Research
The benthic biolayer is a shallow zone of reactive streambed sediments, widely believed to contribute disproportionately to whole‐stream reactions such as aerobic respiration and contaminant transformation.
Kevin R. Roche, Marco Dentz, Ryan M. Samolis, Jase L. Hixson, Ricardo González‐Pinzón, Skuyler P. Herzog, Junyeol Kim, Adam S. Ward, Diogo Bolster   +8 more
doaj   +1 more source

Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains

BMC Microbiology, 2018
Background Biofilms are formed by a complex bacterial community encapsulated by a polymeric matrix, with strong adherent properties and persistent phenotype. Biofilms are considered one of the most challenging areas of modern medicine.
Cristina D. Cruz, Shreya Shah, Päivi Tammela   +2 more
doaj   +1 more source

Biocompatible (Nano)Composites Based on Poly(ε‐Caprolactone)/Siloxene

Polymer Engineering &Science, EarlyView.
Bio‐inert and biocompatible pCLO/siloxene (nano)composites with enhanced mechanical properties. ABSTRACT The work focuses on the synthesis of the siloxene nanofiller and its subsequent use in the preparation of poly(ε‐caprolactone)/siloxene (nano)composites via in situ polymerization and melt blending.
Lucie Reinšteinová, Václava Benešová, Nikola Slepičková Kasálková, Jan Kočí, Jiří Brožek, Jonáš Uřičář   +5 more
wiley   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

The Use of Baker’s Yeast in the Resazurin Reduction Test: A Simple, Low-Cost Method for Determining Cell Viability in Proliferation and Cytotoxicity Assays

Journal of Microbiology & Biology Education, 2018
Cell viability assays require expensive commercial testing kits and sophisticated cell culture techniques. Thus, a laboratory activity for testing the cellular proliferative and cytotoxic effects of certain substances using baker’s yeast (Saccharomyces ...
Jayzon G. Bitacura
doaj   +1 more source

Stability studies of cynaropicrin–major sesquiterpene lactone of Cynara cardunculus leaves

Pest Management Science, EarlyView.
This study investigated its stability under high temperature and pH, mimicking agronomic extremes and under soil context. Bioassays demonstrated that degradation products exhibited higher phytotoxic activity than cynaropicrin and deacylcynaropicrin. This is the first study about cynaropicrin's stability, characterizing degradation products, and their ...
Daniela Rosa, Carlos Rial, José MG Molinillo, Alejandro Sampalo, Rosa M Varela, Francisco A Macías, Maria F Duarte   +6 more
wiley   +1 more source