Results 91 to 100 of about 322,552 (311)

Two multi-linked rescue robots: design, construction and field tests

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
Rescue robots that can penetrate into narrow gaps in the rubble, create and maintain spaces for rescuers after earthquakes are urgently needed in search and rescue missions.
Xizhe ZANG   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Preparing to be unprepared – training for Mass Rescue Operations

open access: yes, 2019
“Preparing to be unprepared” might be considered as a contradiction in terms, but is in the case of maritime mass rescue operations (MRO) vital to be able to save lives.
Axvi, Lars,, Forsman, Fredrik,
core  

Analysis of Equipment for Rescue Boat at Rescue Ships in Terms of Safety of the Victim

open access: yesScientific Journal of Gdynia Maritime University, 2017
The article analyzes the fast rescue boat equipment required in the fifth chapter of the LSA Code for suitability in rescue operations on the basis of the rescue action conducted by Maritime Search and Rescue Service.
P. Krajewska
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Toward a Behavioral Ecology of Rescue Behavior

open access: yesEvolutionary Psychology, 2013
Although the study of helping behavior has revolutionized the field of behavioral ecology, scientific examination of rescue behavior remains extremely rare, except perhaps in ants, having been described as early as 1874.
Karen L. Hollis, Elise Nowbahari
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Acute Homelessness: Care through rescue service and social work

open access: yes, 2023
Ausgangslage Akut wohnungslose Menschen sind im österreichischen Gesundheitssystem von Ausgrenzung betroffen. Meist werden nur kurz medizinische Symptome gelindert. Eine Anbindung an Soziale Arbeit findet nicht systematisch statt, könnte allerdings eine
Redelsteiner, Samuel
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Transfer of undertakings: the tension between business rescue and employment protection in corporate insolvency

open access: yes, 2012
Where a business becomes insolvent and its rescue is predicated on a going concern sale or transfer to another employer, there is a tension between employee protection and the rescue of insolvent but viable businesses. There is a consensus that employees
Etukakpan, SE
core  

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