Results 111 to 120 of about 322,552 (311)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Mine Rescue Station Group Practicing
, 1942 A man with bandages on his head and arm is tied to a stretcher. His head rests on folded blankets.
Martin's Photo Shop
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Unknown Cost: The Psychological Implications of Animal Rescue Work
, 2020 Tens of thousands of abandoned and orphaned animals are taken in by rescue organizations across Canada every year. These animals are then rehabilitated by caring individuals who often work as volunteers.
Belland, Stephanie
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International Journal of Nursing SciencesObjective: This study aimed to investigate the factors influencing nurses’ ability to respond to public health emergencies and understand the relationship between nurses’ ability to respond to emergencies and workplace resilience.
Wenwen Shi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Methods of Performing Rescue Work In Slope Processes Affected Areas
Because of various reasons in naturally as well as in artificially formed slopes the rosks can lose their stability and, under the influence of gravitational force, move down, forming landslides, screes and earth creeps.[1] Such processes are classified ...
Jemeļjanovs, Vladimirs +3 more
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Physical capacity of rescue personnel in the mining industry
, 2008 Background The mining industry has one of the highest occupational rates of serious injury and fatality. Mine staff involved with rescue operations are often required to respond to physically challenging situations.
Parker, Tony W. +15 more
core +1 more source