Results 111 to 120 of about 881,422 (304)

Thinking on medical emergency rescue work against liquid propellant accidents

open access: yesZhiye weisheng yu yingji jiuyuan, 2023
QU Mingyue, GUO Baoshi
doaj   +1 more source

Dangerous calling, the life-and-death matter of safety at sea: a collection of articles from SAMUDRA Report [PDF]

open access: yes, 2003
Fishing is arguably the world's most dangerous vocation, reporting the highest rate of occupational fatalities among industries, made only worse by declining fish prices, overfished waters and shortened fishing seasons.

core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Research on the relationship between nurses’ emergency public health response capacity and workplace resilience: A cross-sectional study

open access: yesInternational Journal of Nursing Sciences
Objective: This study aimed to investigate the factors influencing nurses’ ability to respond to public health emergencies and understand the relationship between nurses’ ability to respond to emergencies and workplace resilience.
Wenwen Shi   +4 more
doaj   +1 more source

Pelastussuunnitelma : Sirkkalantie 12 B, Teräspalvelukeskus Riikonen Oy [PDF]

open access: yes, 2012
Lopputyön aiheena oli laatia pelastussuunnitelma konepajateollisuutta harjoittavan Konekorjaamo Riikonen Oy:n Sirkkalan yksikölle, Teräspalvelukeskukselle. Yksikössä työskentelee noin 15 työntekijääja neljä toimihenkilöä. Pääprosessit ovat plasmaleikkaus,
Kantelinen, Erno
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

[Alternative experiences rescuing knowledge for working processes in health].

open access: yesRevista da Escola de Enfermagem da U S P, 2012
O presente trabalho trata-se de um estudo descritivo de abordagem qualitativa, que objetivou compreender o processo de trabalho de enfermeiros e médicos da Estratégia Saúde da Família (ESF), do município de João Pessoa-PB, e identificar as estratégias e táticas alternativas desenvolvidas.
Oliveira, Ana Karla Sousa de   +4 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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