Results 91 to 100 of about 51,656,893 (291)

Summary of Research 2001, Department of Operations Research [PDF]

, 2001
The views expressed in this report are those of the authors and do not reflect the official policy or position of the Department of Defense or U.S.
Faculty of the Department of Operations Research, Naval Postgraduate School
core   +1 more source

Use of post-event surveys of impacts on railways for the evaluation of the IRIP method for surface runoff mapping

E3S Web of Conferences, 2016
IRIP – Indicator of Intense Pluvial Runoff (French Acronym) – is a method to map the susceptibility of territories to surface runoff generation, transfer and accumulation.
Lagadec Lilly-Rose, Breil Pascal, Chazelle Blandine, Braud Isabelle, Moulin Loïc   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

University management: Technology for monitoring the reputation of an educational brand

Образование и наука
Introduction. The processes of formation of a multipolar world lead to changes in higher education. An important consequence of the ongoing changes is the reorientation of the activities of universities to the domestic market, the development of new ...
T. D. Sinyavets, E. A. Luneva, N. V. Katunina   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Advancing genomics research in Ireland. Irish Health Research Forum report and recommendations [PDF]

, 2021
This report presents the proceedings of the Irish Health Research Forum meeting on Thursday 12th November 2020 and makes key recommendations for for advancing genomics research in ...
Health Research Charities Ireland
core  

Theophylline impact on weaning in oxygen-dependent infants followed in an outpatient Kangaroo Program

Frontiers in Pediatrics
BackgroundTheophylline was an orally administered xanthine used for treatment of apnea of prematurity and Bronchopulmonary Dysplasia in ambulatory follow-up of Low-Birth-Weight infants (LBWI) with oxygen-dependency in the outpatient Kangaroo Mother Care ...
Adriana Montealegre-Pomar, Adriana Montealegre-Pomar, Adriana Montealegre-Pomar, Nathalie Charpak, Catalina Lince-Rivera, Catalina Lince-Rivera   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source