Results 231 to 240 of about 70,430,026 (358)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Challenges underlying radiology's research problem. [PDF]

open access: yesInsights Imaging
Martí-Bonmatí L   +3 more
europepmc   +1 more source

Sex differences in renal mitochondrial function: a hormone-gous opportunity for research

open access: green, 2020
Regina F. Sultanova   +4 more
openalex   +2 more sources

"Rainbow warriors" [PDF]

open access: yes, 1998
Research, Update
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

A conversation with Dr. Kevin Magnaye, Data Scientist, Caris Life Sciences

open access: yesJournal of Clinical and Translational Science
Clinical Research Forum
doaj   +1 more source

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