Results 131 to 140 of about 59,223,825 (281)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Top Tier 2.0: Research, Scholarship, and Creative Activity

open access: yes
Research, scholarship, and creative activity are all integral to the university. Our efforts focus on increasing innovation and excellence in research, with multiple interdisciplinary opportunities, especially those opportunities that capitalize on ...
University of Nevada, Las Vegas
core  

UA35 Newsletter, Issue #2 [PDF]

open access: yes
Newsletter created by and about the WKU Office of Research & Creative ...
WKU Research & Creative Activity
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RESEARCH ACTIVITIES

open access: yesJOURNAL of the JAPANESE SOCIETY of AGRICULTURAL MACHINERY, 2008
  +6 more sources

Cancer research activity in the Arab world: a 15-year bibliometric analysis. [PDF]

open access: yesJ Egypt Public Health Assoc, 2022
Machaalani M   +3 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Associations between quality of life, physical activity, and sedentary behaviour : an examination of continuous and bout measures of activity and sedentary behaviour from the Walk 2.0 trial

open access: yes, 2015
Objective: The health benefits of physical activity participation and minimising sedentary behaviours are well known. As well, evidence exists for the relationship between physical activity and health-related quality of life.
Duncan, Mitch J.   +7 more
core  

Governance of Research in the HSE and HSE-Funded Healthcare Services: a scoping report [PDF]

open access: yes, 2019
A significant level of health research activity is currently on-going in the Health Service Executive (HSE) and associated organisations, and a wide range of clinical and non-clinical staff members are engaged in this activity. However, a review of the
Research and Development
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