Results 141 to 150 of about 59,223,825 (281)

THE ORGANIZATION OF SECONDARY SCHOOL STUDENTS’ RESEARCH ACTIVITIES IN THE COURSE OF SUBJECT-ORIENTED TRAINING

open access: yesВестник Кемеровского государственного университета, 2013
In article investigates the problems of modern education, and in the way of a solution, describes the experience of orgasnising secondary school students’ research activities in the course of subject-oriented training and preparatory training.
R. S. Fomichev
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Results From the Netherlands' 2018 Report Card on Physical Activity for Children and Youth

open access: yes, 2018
National surveillance data in the Netherlands show that the percentage of children and youth, who meet the Dutch physical activity guidelines has decreased significantly between 2006 and 2014.1 Data from the 2016 Dutch Physical Activity Report Card ...
Takken, Tim   +2 more
core  

Randomised controlled trials evaluating anticancer therapies in haematological cancers: an overview of global research activity. [PDF]

open access: yesEcancermedicalscience, 2023
Sengar M   +10 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland. [PDF]

open access: yesViruses, 2022
Żaczek M   +5 more
europepmc   +1 more source

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