Results 71 to 80 of about 1,515,548 (304)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Understanding SME policy environment in ASEAN

open access: yes, 2014
Quality of institutions is strongly positively correlated with other policy performance indicators. More needs to be done to overcome the barriers to SMEs’ competitiveness and productivity given regional integration.
Vathana, Roth
core  

The next steps : an independent review of sustainable development in the English regions [PDF]

open access: yes, 2012
Summarised in 'The next steps : an independent review of sustainable development in the English regions : executive summary'.The Sustainable Development Commission's independent review of the progress of sustainable development in the English regions ...
Sustainable Development Commission
core   +2 more sources

Commodity Revenues, Agricultural Sector and the Magnitude of Deindustrialization: A Novel Multisector Perspective

open access: yesEconomies, 2019
This study puts forward a model of a multisector economy and embeds it in a novel theoretical framework to address the relationship between commodity revenues and manufacturing output with a special focus on the role of the agricultural sector. The three-
Elkhan Richard Sadik-Zada   +2 more
doaj   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus   +2 more
wiley   +1 more source

The changing Aboriginal and Torres Strait Islander population: evidence from the 2006–11 Australian Census Longitudinal Dataset [PDF]

open access: yes, 2015
Populations change and grow through time. Keeping track of this change and associated improvements or worsening in outcomes is a key role for statistical agencies and researchers, and is necessary for an informed and evidence-based policy debate. This is
Nicholas Biddle   +3 more
core  

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Founding Editorial: Neuro‐Drug Discovery

open access: yes
Neuro-Drug Discovery, EarlyView.
Wenbin Li
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Tanzania Africa Research in Sustainable Intensification for the Next Generation (Africa RISING) Baseline Evaluation Survey

open access: yes, 2014
As part of the US government’s Feed the Future initiative that aims to address global hunger and food security issues in sub-Saharan Africa, the US Agency for International Development is supporting three multi-stakeholder agricultural research projects ...
International Food Policy Research Institute (IFPRI)
core   +1 more source

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