Results 71 to 80 of about 1,515,548 (304)
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Understanding SME policy environment in ASEAN
Quality of institutions is strongly positively correlated with other policy performance indicators. More needs to be done to overcome the barriers to SMEs’ competitiveness and productivity given regional integration.
Vathana, Roth
core
The next steps : an independent review of sustainable development in the English regions [PDF]
Summarised in 'The next steps : an independent review of sustainable development in the English regions : executive summary'.The Sustainable Development Commission's independent review of the progress of sustainable development in the English regions ...
Sustainable Development Commission
core +2 more sources
This study puts forward a model of a multisector economy and embeds it in a novel theoretical framework to address the relationship between commodity revenues and manufacturing output with a special focus on the role of the agricultural sector. The three-
Elkhan Richard Sadik-Zada +2 more
doaj +1 more source
Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus +2 more
wiley +1 more source
The changing Aboriginal and Torres Strait Islander population: evidence from the 2006–11 Australian Census Longitudinal Dataset [PDF]
Populations change and grow through time. Keeping track of this change and associated improvements or worsening in outcomes is a key role for statistical agencies and researchers, and is necessary for an informed and evidence-based policy debate. This is
Nicholas Biddle +3 more
core
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Founding Editorial: Neuro‐Drug Discovery
Neuro-Drug Discovery, EarlyView.
Wenbin Li
wiley +1 more source
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon +9 more
wiley +1 more source
As part of the US government’s Feed the Future initiative that aims to address global hunger and food security issues in sub-Saharan Africa, the US Agency for International Development is supporting three multi-stakeholder agricultural research projects ...
International Food Policy Research Institute (IFPRI)
core +1 more source

