Results 81 to 90 of about 46,037,565 (314)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Exploring Phrasal Complexity Features in Graduate Students’ Data Commentaries and Research Articles [PDF]

open access: yesJournal of English Language Teaching and Learning, 2019
The present study aimed at exploring phrasal complexity features in data commentaries produced by graduate students and in research articles written by expert writers.
Alireza Jalilifar   +2 more
doaj  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

RHETORICAL MOVES IN INTRODUCTIONS: PROMPT-BASED WRITING TRIAL RESULTS

open access: yesLanguage Literacy: Journal of Linguistics, Literature, and Language Teaching
This study investigates the role of writing prompts to create appropriate introduction section in research article. The study analyzes three texts generated from ChatGPT by using three distinct prompts formulated based on the writing prompt model ...
Rohani Ganie   +3 more
doaj   +1 more source

The journal article incubator approach to teaching writing skills and enhancing research outputs

open access: yes, 2012
The journal article incubator approach to teaching writing skills to researchers and academics involves a series of engaging and inclusive workshops in which best practice writing, reviewing and rewriting skills are modelled by the presenters and ...
Retief, F.   +2 more
core  

Evaluating a research article

open access: yes, 1994
If practice is to be research-based, midwives need to be able to understand a research article quickly and efficiently. This article gives simple guidelines to help you consider some of the main elements involved in critiquing an article.
Colin Rees
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Conceptualisations of sex and gender in oral health research

open access: yes
Sex and gender are widely recognised as determinants of health, influencing general and oral health outcomes. In this conceptual article, we argue that the potential of sex- and gender-based oral health research to deliver transformative insights into ...
Neville, P, Muirhead, V
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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