Results 141 to 150 of about 115,977,507 (339)
, 2016 [[abstract]]Recently, the concept of \#8220;cancer stem cell\#8221; may renew the notion of designing cancer therapy. The progression and relapse of tumor may be initiated by the remaining cancer stem cells that escaped from conventional cancer ...
Yao, CJ;Yeh, CT;Yeh, CF;Chang, CK;Li, CH;Yan, JL;Chuang, SE;Lai, GM
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GDPR and health research: stakeholder voices. Data protection and health research - what does the legislation mean for patients, the public and the research community? Report and recommendations. [PDF]
, 2018 This report presents the proceedings of the Irish Health Research Forum on November 14th 2018 focusing on data protection legislation and health research, and the implications for patients, the public and researchers.
Medical Research Charities Group
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
, 2016 [[abstract]]The aryl hydrocarbon receptor nuclear translocator (ARNT) is widely involved in regulating the tumorigenesis process by inducing genes that are involved in tumor growth and angiogenesis.
Huang, CR;Lee, CT;Chang, KY;Chang, WC;Chen, BK
core +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Mutually exclusive expression of SOX2 and SOX9 in lung adenocarcinoma cells and its implications
, 2016 [[abstract]]SOX family genes play critical roles in embryonic development, cell fate determination, differentiation, and proliferation. Some members of the SOX family, including SOX2 and SOX9, have been shown as hall marks of lung cancers. However, their
Jiang, SS;Fang, WT;Chang, IS;Huang, CT
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source