Results 151 to 160 of about 5,985,633 (306)

Neural Mechanisms for Information Compression by Multiple Alignment, Unification and Search [PDF]

, 2003
This article describes how an abstract framework for perception and cognition may be realised in terms of neural mechanisms and neural processing. This framework — called information compression by multiple alignment, unification and search (ICMAUS ...
Wolff, Dr J G
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Some Personal Advice Concerning How to Write Precise, Concise and Eloquent Research Articles

Frontiers in Sports and Active Living, 2021
Hans-Christer Holmberg, Hans-Christer Holmberg, Billy Sperlich   +2 more
doaj   +1 more source

Grounded theory: experiences of two studies with a focus on axial coding and the use of the NVivo qualitative analysis software [PDF]

, 2010
This article recounts personal experience of one of the analytical steps followed in Grounded Theory Methodology (GTM), based on the empirical experience and theoretical knowledge of a tourism and an information technology researcher. The research aim of
Gorra, A, Kornilaki, M
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Philosophical stances in information systems research: a case analysis and critical reflection

Humanities & Social Sciences Communications
This article presents an overview of and introduction to philosophical stances often identified in information systems research. The philosophical stances are described regarding their ontology, epistemology and axiology across the philosophical ...
Peter André Busch
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Teaching research integrity: a manual of good practices: an outline

International Journal for Educational Integrity
This article addresses the critical need for effective teaching strategies in research integrity (RI), acknowledging widespread uncertainty among educators on the best approach.
Håkan Salwén, Cyril Holm, Gerald Achermann, Muhammad Asaduzzaman, Fenneke Blom, Agnieszka Dwojak-Matras, Lucianne Groenink, Bernadette Gruber, Mariëtte van den Hoven, Dragana Ignjatovic Ristic, Ron Iphofen, Julia Priess-Buchheit   +11 more
doaj   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source