Results 121 to 130 of about 3,460,507 (274)

Climbing Atop the Shoulders of Giants: The Impact of Institutions on Cumulative Research [PDF]

open access: yes
While the cumulative nature of knowledge is recognized as central to economic growth, the microeconomic foundations of cumulativeness are less understood.
Scott Stern, Jeffrey L. Furman
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Research and Science Today 1(19)/2020

open access: yes
RESEARCH AND SCIENCE TODAY is a biannual science journal established in 2011. The journal is an informational platform that publishes assessment articles and the results of various scientific research carried out by academics.
Journal, Research and Science Today
core   +1 more source

Teaching writing of scientific abstracts in English: CLIL methodology in an integrated English and Medicine course [PDF]

open access: yesIbérica, 2010
In the I Faculty at the University of Rome “La Sapienza” Medical School, one of the several methodology courses aims at developing approaches by physicians to patient queries.
Philippa Mungra
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Innovations in structuring article introductions: The case of Applied Linguistics [PDF]

open access: yesIbérica, 2014
This study explores the rhetorical structure of introductions that are followed by an independent Literature Review (L) section. It is motivated by an increasing use or even the prevalent use of both the introduction and L sections in the opening phase ...
Ling Lin
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Amended Articles of Incorporation and By-Laws of the International Rice Research Institute

open access: yes, 1982
Amended articles of incorporation dated October 1982 and amended by-laws dated September 17, 1993 for the International Rice Research Institute. The amendment to the articles of incorporation amends sections 1, 2, 3, 4, 6, 7 and adds a ninth section on ...
International Rice Research Institute
core  

Traditional Chinese Medicine (TCM) research articles unpacked: a systemic functional linguistics (SFL) elemental genre approach

open access: yesCogent Arts & Humanities
Over the past two decades, extensive research has been conducted on the rhetorical structure of research articles (RAs) from the English for Specific Purposes (ESP) genre approach.
Lin Zhao, Pramoolsook Issra
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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