Results 161 to 170 of about 29,857,715 (400)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Examining “Salami slicing” publications as a side-effect of research performance evaluation: An empirical study

open access: yesJournal of Data and Information Science
This study investigates whether publication-centric incentive systems, introduced through the National Scientific Accreditation (ASN: Abilitazione Scientifica Nazionale) for professorships in Italy in 2012, contribute to adopting “salami publishing ...
D’Angelo Ciriaco Andrea
doaj   +1 more source

Development and validation for research assessment of Oncotype DX® Breast Recurrence Score, EndoPredict® and Prosigna®. [PDF]

open access: yesNPJ Breast Cancer, 2021
Buus R   +12 more
europepmc   +1 more source

Open Access Scientometrics and the UK Research Assessment Exercise

open access: yes, 2007
Scientometric predictors of research performance need to be validated by showing that they have a high correlation with the external criterion they are trying to predict.
Harnad, Stevan
core   +2 more sources

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Legal Research Assessment

open access: yesLegal Reference Services Quarterly, 2009
Legal research instructors seek to provide their students with a working knowledge of important research tools, strategies with which to develop a rational research plan, and the skill to conduct research efficiently, among other things. A well-conceived legal research class may utilize short-answer assignments, quizzes, and scavenger hunt exercises as
openaire   +2 more sources

A QUANTITATIVE SURVEY ANALYSIS OF ELEMENTARY PRESERVICE TEACHER PERCEPTIONS OF ASSESSMENT TASKS IN SCIENCE COURSEWORK [PDF]

open access: yes, 2017
This replication survey research study sought to further understand preservice elementary teachers’ perceptions of assessment tasks they encountered in secondary science coursework. Students are assessed through informal and formal assessments, including
Killingsworth, Allison D
core   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

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