Results 61 to 70 of about 29,857,715 (400)
eLife is conducting a trial in which authors will decide how to respond to the issues raised during peer review.
Mark Patterson, Randy Schekman
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FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Five years after eLife published its first papers, we reflect on our consultative approach to peer review, the challenges of reproducibility, and the need to reform how published research is assessed.
Randy Schekman
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Inefficiency in selecting products for submission to national research assessment exercises [PDF]
One of the critical issues in national research assessment exercises concerns the choice of whether to evaluate the entire scientific portfolio of the institutions or a subset composed of the best products.
G. Abramo+2 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
This paper presents a comparative benchmarking of scientometric indicators to characterize the patterns of publication and research performance at the country level, in a specific field (nanoscience and nanotechnology) during the period 2003–2013.
Zaida Chinchilla-Rodríguez+4 more
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Data reuse is a common practice in the social sciences. While published data play an essential role in the production of social science research, they are not consistently cited, which makes it difficult to assess their full scholarly impact and give ...
Sara Lafia+4 more
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CRUK Basic and Clinical Research DMP Assessment Rubric v2.0 [PDF]
This rubric is intended to assist in the assessment of CRUK Basic and Clinical Research data management plans, against the criteria required by the funder.
Donaldson, Mary
core +2 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
The Italian Research Assessment Exercises
Italian universities have so far experienced three assessment exercises (2001-3, 2004-10 and 2011-14). The fiscal law approved in December 2016 dictates that from now onwards the reference periods will be quinquennial, reducing the discretionary power so
Daniele Checchi
doaj