Results 131 to 140 of about 15,898,430 (313)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
G²LM|LIC - Labor Supply Complementarities in Urban Côte d‘Ivoire
This data examines complementarities in labor supply: to what extent does a person’s desire to work at a firm depend on whether others in her social network also work at the firm? The researchers conducted two field experiments in urban Côte d’Ivoire.
Donald, Aletheia, Grosset, Florian
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Do-It-Yourself Research Data Management Training Kit for Librarians
, 2013 The DIY Research Data Management Training Kit for Librarians is a pilot RDM course for aimed at librarians covering five topics involving reading assigments from the MANTRA course (http://datalib.edina.ac.uk/mantra/), reflective writing, and 2-hour face ...
EDINA and Data Library, University of Edinburgh
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Adoption of an electronic patient record sharing pilot project: cross-sectional survey
This data archive contains the data that supplement the manuscript in Journal of Medical Internet Research titled “Adoption of an electronic patient record sharing pilot project: cross-sectional survey”.
Wang, Jingxuan +5 more
core +1 more source
Big Research Data and Data Science
Data Science Journal, 2015 يهدف المؤتمر إلى تحسين فهم القضايا المركزية في عصر البيانات الضخمة، وتعزيز التواصل والتعاون متعدد التخصصات، والمساعدة في تطوير علماء البيانات الشباب، وتشجيع تنشيط مناهج البحث التقليدية والمساهمة في الاستراتيجية الوطنية الصينية لتعزيز الابتكار ودعمها. في جميع أنحاء العالم، هناك حديث عن "ثورة البيانات" – يهدف هذا المؤتمر إلى وضع الصين في طليعة هذه الثورة،
openaire +4 more sources