Results 161 to 170 of about 74,522,906 (314)
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Do-It-Yourself Research Data Management Training Kit for Librarians
The DIY Research Data Management Training Kit for Librarians is a pilot RDM course for aimed at librarians covering five topics involving reading assigments from the MANTRA course (http://datalib.edina.ac.uk/mantra/), reflective writing, and 2-hour face ...
EDINA and Data Library, University of Edinburgh
core
Data for preparing the captioned manuscript that has been published in the International Journal of Environmental Research and Public ...
So, Winnie Kwok Wei +4 more
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
IFPRI-CCAFS Gender and Climate Change Survey Data: Bangladesh
The IFPRI-CCAFS Gender and Climate Change Survey data were collected between April and May 2013 as part of the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS) under the project "Increasing Women’s Resilience to Confront ...
International Food Policy Research Institute (IFPRI)
core +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Replication dataset and code for: Liang, H. (2021). Decreasing social contagion effects in diffusion cascades: Modeling message spreading on social media. Telematics and Informatics. https://doi.org/10.1016/j.tele.2021.101623 Using preprocess.r (R code)
Liang, Hai
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

