Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Data Management and Sharing Plan for: NHLBI Data Stage Coordinating Center (STAGECC) [PDF]
The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project ...
Krishnamurthy, Ashok
core +1 more source
Research data management needs assessment for social sciences graduate students: A mixed methods study. [PDF]
Zhou X, Xu Z, Kogut A.
europepmc +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Data Management and Sharing Plan for: Common Data Elements (CDE) for Kidney Diseases [PDF]
The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project ...
Haendel, Melissa
core +1 more source
The genotype list string code syntax for exchanging nomenclature-level genotyping results in clinical and research data management and analysis systems. [PDF]
Mack SJ +7 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Data Management and Sharing Plan for: Developing Data-Driven Clinical Signatures for People Who Experience Hallucinations [PDF]
The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project ...
Buck, Ben
core +1 more source
Research data management for bioimaging: the 2021 NFDI4BIOIMAGE community survey. [PDF]
Schmidt C +6 more
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

