Results 141 to 150 of about 654,709 (293)

Acceleron: A Tool to Accelerate Research Ideation [PDF]

arXiv
Several tools have recently been proposed for assisting researchers during various stages of the research life-cycle. However, these primarily concentrate on tasks such as retrieving and recommending relevant literature, reviewing and critiquing the draft, and writing of research manuscripts.
arxiv  

Design of Research Reactors, Especially About a Water Boiler Type Reactor

, 1956
Masakichi MATSUMOTO, Schoichi HIRAYAMA
openalex   +2 more sources

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Guiding Principles for Using Mixed Methods Research in Software Engineering [PDF]

arXiv
Mixed methods research is often used in software engineering, but researchers outside of the social or human sciences often lack experience when using these designs. This paper provides guiding principles and advice on how to design mixed method research, and to encourage the intentional, rigorous, and innovative application of mixed methods in ...
arxiv  

240) Experimental Research on Ultimate Load Design of Shell Roofs (Part 4)(Civil Engineering)

, 1956
Wataru Kato, Akira Enami
openalex   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

3065) Study on the research Informartion Service System (Research manegiment work, manegiment Consaltant work, Industrial eng & Operations research group member work etc.) for decision making on the Shopping Design(Scientific Basis of Planning Building)

, 1959
Kiichiro Kobayashi
openalex   +2 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

3071) Study on the Research Management Technique for Design Activity of a House : technique of measurement to a matter of taste to house plane(Scientific Basis of Planning Building)

, 1958
Kiichiro Kobayashi, Kozaburo Fukuchi
openalex   +2 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source